Cardiovascular diseases (CVDs), such as ischaemic heart disease, cardiomyopathy,
atherosclerosis, hypertension, stroke and heart failure, are among the leading causes of …

The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point …

Stroke constitutes the second leading cause of death and a major cause of disability
worldwide. Stroke is normally classified as either ischemic or hemorrhagic stroke (HS) …

In myocardial ischemia/reperfusion injury (MIRI), moderate mitophagy is a protective or
adaptive mechanism because of clearing defective mitochondria accumulates during MIRI …

Ischemia-reperfusion injury (IR injury), produced by initial interruption and subsequent
restoration of organ blood flow, is an important clinical dilemma accompanied by various …

Abstract FUN14 domain-containing protein 1 (Fundc1)-dependent mitophagy, mainly
activated by ischemic/hypoxic preconditioning, benefits acute myocardial reperfusion injury …

Physical exercise promotes cardiorespiratory fitness, and is considered the mainstream of
non-pharmacological therapies along with lifestyle modification for various chronic diseases …

Lipopolysaccharide (LPS) from Gram-negative bacteria is a major contributor to
cardiovascular failure, but the signaling mechanisms underlying its stress response are not …

Recent advances in medical technology and health care have greatly improved the
management for chronic diseases and prolonged human lifespan. Unfortunately, increased …

Western lifestyle contributes to an overt increase in the prevalence of metabolic anomalies
including diabetes mellitus (DM) and obesity. Prevalence of DM is rapidly growing …