miRNA: a promising therapeutic target in cancer

A Menon, N Abd-Aziz, K Khalid, CL Poh… - International journal of …, 2022 - mdpi.com
microRNAs are small non-coding RNAs that regulate several genes post-transcriptionally by
complementarity pairing. Since discovery, they have been reported to be involved in a …

Applications of graphene and graphene oxide in smart drug/gene delivery: is the world still flat?

M Hoseini-Ghahfarokhi, S Mirkiani… - International Journal …, 2020 - Taylor & Francis
Graphene, a wonder material, has made far-reaching developments in many different fields
such as materials science, electronics, condensed physics, quantum physics, energy …

Engineered extracellular vesicles as intelligent nanosystems for next-generation nanomedicine

Z Fan, C Jiang, Y Wang, K Wang, J Marsh… - Nanoscale …, 2022 - pubs.rsc.org
Extracellular vesicles (EVs), as natural carriers of bioactive cargo, have a unique
micro/nanostructure, bioactive composition, and characteristic morphology, as well as …

A near‐infrared photo‐switched MicroRNA amplifier for precise photodynamic therapy of early‐stage cancers

Y Zhang, W Chen, Y Zhang, X Zhang… - Angewandte Chemie …, 2020 - Wiley Online Library
Stimuli‐responsive photodynamic therapy (PDT) is a hot topic in precise medicine, but the
low abundance of responsive trigger molecules in early‐stage disease limits application …

Emerging approaches for graphene oxide biosensor

J Kim, SJ Park, DH Min - Analytical chemistry, 2017 - ACS Publications
Graphene is a 2D material that has a honeycomb-like structure consisting of single sp2
carbon layers and was first isolated from graphite in 2004. 1 It has drawn much attention …

Graphene oxide-based fluorescent biosensors and their biomedical applications in diagnosis and drug discovery

Y Yim, H Shin, SM Ahn, DH Min - Chemical Communications, 2021 - pubs.rsc.org
Graphene oxide (GO), an oxidized derivative of graphene, has received much attention for
develo** novel fluorescent bioanalytic platforms due to its remarkable optical properties …

A Photosensitized Singlet Oxygen (1O2) Toolbox for Bio-Organic Applications: Tailoring 1O2 Generation for DNA and Protein Labelling, Targeting and Biosensing

D Aerssens, E Cadoni, L Tack, A Madder - Molecules, 2022 - mdpi.com
Singlet oxygen (1O2) is the excited state of ground, triplet state, molecular oxygen (O2).
Photosensitized 1O2 has been extensively studied as one of the reactive oxygen species …

Evolution of complexity in non-viral oligonucleotide delivery systems: from gymnotic delivery through bioconjugates to biomimetic nanoparticles

K Bakowski, S Vogel - RNA biology, 2022 - Taylor & Francis
From the early days of research on RNA biology and biochemistry, there was an interest to
utilize this knowledge and RNA itself for therapeutic applications. Today, we have a series of …

Dual MicroRNA-triggered drug release system for combined chemotherapy and gene therapy with logic operation

R Yue, M Chen, N Ma - ACS applied materials & interfaces, 2020 - ACS Publications
Combination therapy via stimulus-responsive drug release is known to improve treatment
efficacy and minimize side effects. However, the use of low-abundance cancer biomarkers …

Multifunctional delivery systems for peptide nucleic acids

S Volpi, U Cancelli, M Neri, R Corradini - Pharmaceuticals, 2020 - mdpi.com
The number of applications of peptide nucleic acids (PNAs)—oligonucleotide analogs with a
polyamide backbone—is continuously increasing in both in vitro and cellular systems and …