Humanized mice in translational biomedical research

LD Shultz, F Ishikawa, DL Greiner - Nature Reviews Immunology, 2007 - nature.com
The culmination of decades of research on humanized mice is leading to advances in our
understanding of human haematopoiesis, innate and adaptive immunity, autoimmunity …

[PDF][PDF] Adult stem cells: hopes and hypes of regenerative medicine

J Dulak, K Szade, A Szade, W Nowak… - Acta Biochimica …, 2015 - ruj.uj.edu.pl
Stem cells are self-renewing cells that can differentiate into specialized cell type (s).
Pluripotent stem cells, ie embryonic stem cells (ESC) or induced pluripotent stem cells …

Rational design of bisphosphonate lipid-like materials for mRNA delivery to the bone microenvironment

L Xue, N Gong, SJ Shepherd, X ** to repair the kidney and improve function in acute renal failure
M Morigi, B Imberti, C Zoja, D Corna… - Journal of the …, 2004 - journals.lww.com
Injury to a target organ can be sensed by bone marrow stem cells that migrate to the site of
damage, undergo differentiation, and promote structural and functional repair. This …

Stem cell origin of cancer and differentiation therapy

S Sell - Critical reviews in oncology/hematology, 2004 - Elsevier
Our forefathers in pathology, on observing cancer tissue under the microscope in the mid-
19th century, noticed the similarity between embryonic tissue and cancer, and suggested …