Cholangiocarcinoma 2020: the next horizon in mechanisms and management
JM Banales, JJG Marin, A Lamarca… - Nature reviews …, 2020 - nature.com
Cholangiocarcinoma (CCA) includes a cluster of highly heterogeneous biliary malignant
tumours that can arise at any point of the biliary tree. Their incidence is increasing globally …
tumours that can arise at any point of the biliary tree. Their incidence is increasing globally …
Targeted therapy for hepatocellular carcinoma
The last 3 years have seen the emergence of promising targeted therapies for the treatment
of hepatocellular carcinoma (HCC). Sorafenib has been the mainstay of treatment for a …
of hepatocellular carcinoma (HCC). Sorafenib has been the mainstay of treatment for a …
Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of …
JM Banales, V Cardinale, G Carpino… - Nature reviews …, 2016 - research.ed.ac.uk
Cholangiocarcinoma (CCA) is a heterogeneous group of malignancies with features of
biliary tract differentiation. CCA is the second most common primary liver tumour and the …
biliary tract differentiation. CCA is the second most common primary liver tumour and the …
Organic cation transporters in health and disease
H Koepsell, LC Daws - Pharmacological reviews, 2020 - Elsevier
The organic cation transporters (OCTs) OCT1, OCT2, OCT3, novel OCT (OCTN) 1, OCTN2,
multidrug and toxin exclusion (MATE) 1, and MATE kidney-specific 2 are polyspecific …
multidrug and toxin exclusion (MATE) 1, and MATE kidney-specific 2 are polyspecific …
Mechanisms of drug resistance in HCC
HCC comprises∼ 80% of primary liver cancer. HCC is the only major cancer for which death
rates have not improved over the last 10 years. Most patients are diagnosed with advanced …
rates have not improved over the last 10 years. Most patients are diagnosed with advanced …
Molecular bases of drug resistance in hepatocellular carcinoma
The poor outcome of patients with non-surgically removable advanced hepatocellular
carcinoma (HCC), the most frequent type of primary liver cancer, is mainly due to the high …
carcinoma (HCC), the most frequent type of primary liver cancer, is mainly due to the high …
Sorafenib resistance in hepatocellular carcinoma: the relevance of genetic heterogeneity
Despite advances in biomedicine, the incidence and the mortality of hepatocellular
carcinoma (HCC) remain high. The majority of HCC cases are diagnosed in later stages …
carcinoma (HCC) remain high. The majority of HCC cases are diagnosed in later stages …
Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)
JM Banales, V Cardinale, G Carpino… - Nature Reviews …, 2016 - nature.com
Cholangiocarcinoma (CCA) is a heterogeneous group of malignancies with features of
biliary tract differentiation. CCA is the second most common primary liver tumour and the …
biliary tract differentiation. CCA is the second most common primary liver tumour and the …
[PDF][PDF] Lusutrombopag for the treatment of thrombocytopenia in patients with chronic liver disease undergoing invasive procedures (L‐PLUS 2)
M Peck‐Radosavljevic, K Simon, A Iacobellis… - …, 2019 - Wiley Online Library
Thrombocytopenia may be associated with increased bleeding risk impacting timing and
outcome of invasive procedures in patients with chronic liver disease (CLD) …
outcome of invasive procedures in patients with chronic liver disease (CLD) …
Mechanisms of resistance to chemotherapy in gastric cancer
Although surgical resection is the standard curative therapy for gastric cancer, these tumors
are often diagnosed at an advanced stage, when surgery is not recommended. Alternative …
are often diagnosed at an advanced stage, when surgery is not recommended. Alternative …