[HTML][HTML] The chemistry of snake venom and its medicinal potential

AL Oliveira, MF Viegas, SL da Silva… - Nature Reviews …, 2022 - nature.com
The fascination and fear of snakes dates back to time immemorial, with the first scientific
treatise on snakebite envenoming, the Brooklyn Medical Papyrus, dating from ancient Egypt …

From animal poisons and venoms to medicines: achievements, challenges and perspectives in drug discovery

KCF Bordon, CT Cologna, EC Fornari-Baldo… - Frontiers in …, 2020 - frontiersin.org
Animal poisons and venoms are comprised of different classes of molecules displaying wide-
ranging pharmacological activities. This review aims to provide an in-depth view of toxin …

Plant-derived toxin inhibitors as potential candidates to complement antivenom treatment in snakebite envenomations

AAX Adrião, AO Dos Santos, EJSP de Lima… - Frontiers in …, 2022 - frontiersin.org
Snakebite envenomations (SBEs) are a neglected medical condition of global importance
that mainly affect the tropical and subtropical regions. Clinical manifestations include pain …

Anticancer activity of toxins from bee and snake venom—An overview on ovarian cancer

MA Moga, OG Dimienescu, CA Arvătescu, P Ifteni… - Molecules, 2018 - mdpi.com
Cancer represents the disease of the millennium, a major problem in public health. The
proliferation of tumor cells, angiogenesis, and the relationship between the cancer cells and …

Preclinical studies of a novel snake venom-derived recombinant disintegrin with antitumor activity: A review

AH Schönthal, SD Swenson, TC Chen… - Biochemical …, 2020 - Elsevier
Snake venoms consist of a complex mixture of many bioactive molecules. Among them are
disintegrins, which are peptides without enzymatic activity, but with high binding affinity for …

Pain modulated by Bothrops snake venoms: Mechanisms of nociceptive signaling and therapeutic perspectives

J dos Santos Cavalcante, FAN Júnior, RJB Jorge… - Toxicon, 2021 - Elsevier
Snake venoms are substances mostly composed by proteins and peptides with high
biological activity. Local and systemic effects culminate in clinical manifestations induced by …

Proteogenomic approaches for snake venom protein-based drug development: current trends and challenges

SK Jhade, K Kalidoss, PK Pathak… - Transactions of The …, 2025 - academic.oup.com
Snake venom proteins have long been recognized for their therapeutic potential.
Proteogenomic strategies, integrating transcriptomics and proteomics, have emerged as …

MultiToxPred 1.0: a novel comprehensive tool for predicting 27 classes of protein toxins using an ensemble machine learning approach

JF Beltrán, L Herrera-Belén, F Parraguez-Contreras… - BMC …, 2024 - Springer
Protein toxins are defense mechanisms and adaptations found in various organisms and
microorganisms, and their use in scientific research as therapeutic candidates is gaining …

[HTML][HTML] Discovery of novel peptide neurotoxins from sea anemone species

J Fu, Y Liao, AH **, B Gao - Frontiers in Bioscience-Landmark, 2021 - imrpress.com
As primitive metazoa, sea anemones are rich in various bioactive peptide neurotoxins.
These peptides have been applied to neuroscience research tools or directly developed as …

Differentiation of snake venom using Raman spectroscopic analysis

V Mozhaeva, V Starkov, D Kudryavtsev… - Journal of Materials …, 2023 - pubs.rsc.org
Snake venoms are complex mixtures of different substances, proteins being their
predominant components. To study the composition of venoms, methods based on …