Pathogenesis of allergic diseases and implications for therapeutic interventions
J Wang, Y Zhou, H Zhang, L Hu, J Liu, L Wang… - Signal transduction and …, 2023 - nature.com
Allergic diseases such as allergic rhinitis (AR), allergic asthma (AAS), atopic dermatitis (AD),
food allergy (FA), and eczema are systemic diseases caused by an impaired immune …
food allergy (FA), and eczema are systemic diseases caused by an impaired immune …
Pulmonary innate immune response determines the outcome of inflammation during pneumonia and sepsis-associated acute lung injury
V Kumar - Frontiers in immunology, 2020 - frontiersin.org
The lung is a primary organ for gas exchange in mammals that represents the largest
epithelial surface in direct contact with the external environment. It also serves as a crucial …
epithelial surface in direct contact with the external environment. It also serves as a crucial …
Innate lymphoid cells and cancer
The innate lymphoid cell (ILC) family is composed of natural killer (NK) cells, ILC1, ILC2 and
ILC3, which participate in immune responses to virus, bacteria, parasites and transformed …
ILC3, which participate in immune responses to virus, bacteria, parasites and transformed …
[HTML][HTML] Innate lymphoid cells: 10 years on
Innate lymphoid cells (ILCs) are lymphocytes that do not express the type of diversified
antigen receptors expressed on T cells and B cells. ILCs are largely tissue-resident cells and …
antigen receptors expressed on T cells and B cells. ILCs are largely tissue-resident cells and …
Mechanisms of dupilumab
The Th2 cytokines interleukin 4 (IL‐4) and IL‐13 and the heterodimeric IL‐4 receptor (IL‐4R)
complexes that they interact with play a key role in the pathogenesis of allergic disorders …
complexes that they interact with play a key role in the pathogenesis of allergic disorders …
[HTML][HTML] Induction of IL-10-producing type 2 innate lymphoid cells by allergen immunotherapy is associated with clinical response
The role of innate immune cells in allergen immunotherapy that confers immune tolerance to
the sensitizing allergen is unclear. Here, we report a role of interleukin-10-producing type 2 …
the sensitizing allergen is unclear. Here, we report a role of interleukin-10-producing type 2 …
Plasticity of innate lymphoid cell subsets
Innate lymphoid cells (ILCs) are important for tissue homeostasis and for the initiation of
immune responses. Based on their transcriptional regulation and cytokine profiles, ILCs can …
immune responses. Based on their transcriptional regulation and cytokine profiles, ILCs can …
Heterogeneity of type 2 innate lymphoid cells
More than a decade ago, type 2 innate lymphoid cells (ILC2s) were discovered to be
members of a family of innate immune cells consisting of five subsets that form a first line of …
members of a family of innate immune cells consisting of five subsets that form a first line of …
S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense
Innate lymphoid cells (ILCs) are innate counterparts of adaptive T lymphocytes, contributing
to host defense, tissue repair, metabolic homeostasis, and inflammatory diseases. ILCs have …
to host defense, tissue repair, metabolic homeostasis, and inflammatory diseases. ILCs have …
Skin-resident innate lymphoid cells converge on a pathogenic effector state
Tissue-resident innate lymphoid cells (ILCs) help sustain barrier function and respond to
local signals. ILCs are traditionally classified as ILC1, ILC2 or ILC3 on the basis of their …
local signals. ILCs are traditionally classified as ILC1, ILC2 or ILC3 on the basis of their …