1. Specific recommendations for prevention strategies often depend on the ischemic
stroke/transient ischemic attack subtype. Therefore, new in this guideline is a section …

Large-vessel vasculitis (LVV) manifests as inflammation of the aorta and its major branches
and is the most common primary vasculitis in adults. LVV comprises two distinct conditions …

Objective To provide evidence‐based recommendations and expert guidance for the
management of giant cell arteritis (GCA) and Takayasu arteritis (TAK) as exemplars of large …

Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are closely related conditions
characterized by systemic inflammation, a predominant IL-6 signature, an excellent …

Background Since the publication of the European League Against Rheumatism (EULAR)
recommendations for the management of large vessel vasculitis (LVV) in 2009, several …

Background China is one of the countries with the highest burden of stroke. Implementing
multidimensional management guidelines will help clinicians practise evidence-based care …

Background Giant-cell arteritis commonly relapses when glucocorticoids are tapered, and
the prolonged use of glucocorticoids is associated with side effects. The effect of the …

Methotrexate, a structural analogue of folic acid, is one of the most effective and extensively
used drugs for treating many kinds of cancer or severe and resistant forms of autoimmune …

Background GCA is a large vessel vasculitis affecting older people, with the highest
incidence among persons 70–79 years of age [1]. Due to forecasted demographic changes …

Objectives To develop treat-to-target (T2T) recommendations in giant cell arteritis (GCA) and
polymyalgia rheumatica (PMR). Methods A systematic literature review was conducted to …