Alternative animal models of aging research
S Holtze, E Gorshkova, S Braude… - Frontiers in Molecular …, 2021 - frontiersin.org
Most research on mechanisms of aging is being conducted in a very limited number of
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …
A review of toxins from Cnidaria
Cnidarians have been known since ancient times for the painful stings they induce to
humans. The effects of the stings range from skin irritation to cardiotoxicity and can result in …
humans. The effects of the stings range from skin irritation to cardiotoxicity and can result in …
A chromosome-scale epigenetic map of the Hydra genome reveals conserved regulators of cell state
JF Cazet, S Siebert, HM Little, P Bertemes… - Genome …, 2023 - genome.cshlp.org
The epithelial and interstitial stem cells of the freshwater polyp Hydra are the best-
characterized stem cell systems in any cnidarian, providing valuable insight into cell type …
characterized stem cell systems in any cnidarian, providing valuable insight into cell type …
Wnt/β-catenin signalling is required for pole-specific chromatin remodeling during planarian regeneration
E Pascual-Carreras, M Marín-Barba… - Nature …, 2023 - nature.com
For successful regeneration, the identity of the missing tissue must be specified according to
the pre-existing tissue. Planarians are ideal for the study of the mechanisms underlying this …
the pre-existing tissue. Planarians are ideal for the study of the mechanisms underlying this …
Model systems for regeneration: Hydra
The freshwater polyp Hydra provides a potent model system for investigating the conditions
that promote wound healing, reactivation of a developmental process and, ultimately …
that promote wound healing, reactivation of a developmental process and, ultimately …
Beyond casual resemblance: rigorous frameworks for comparing regeneration across species
M Srivastava - Annual Review of Cell and Developmental …, 2021 - annualreviews.org
The majority of animal phyla have species that can regenerate. Comparing regeneration
across animals can reconstruct the molecular and cellular evolutionary history of this …
across animals can reconstruct the molecular and cellular evolutionary history of this …
Extracellular vesicle‐enclosed miR‐486‐5p mediates wound healing with adipose‐derived stem cells by promoting angiogenesis
Y Lu, H Wen, J Huang, P Liao, H Liao… - Journal of Cellular …, 2020 - Wiley Online Library
Adipose‐derived stem cells (ASC) are said to have a pivotal role in wound healing.
Specifically, ASC‐secreted extracellular vesicles (EV) carry diverse cargos such as …
Specifically, ASC‐secreted extracellular vesicles (EV) carry diverse cargos such as …
[HTML][HTML] The role of cnidarian developmental biology in unraveling axis formation and Wnt signaling
TW Holstein - Developmental biology, 2022 - Elsevier
Cnidarians are fascinating creatures at the base of metazoan evolution possessing an
almost unlimited regeneration capacity that has attracted the interest of researchers, from …
almost unlimited regeneration capacity that has attracted the interest of researchers, from …
Topology changes of Hydra define actin orientation defects as organizers of morphogenesis
Hydra regenerates one head when cut, but how forces sha** the head are coordinated
remains unclear. Soft compression of Hydra's head-regenerating tissues induces the …
remains unclear. Soft compression of Hydra's head-regenerating tissues induces the …
Mechanical oscillations orchestrate axial patterning through Wnt activation in Hydra
J Ferenc, P Papasaikas, J Ferralli, Y Nakamura… - Science …, 2021 - science.org
Mechanical input shapes cell fate decisions during development and regeneration in many
systems, yet the mechanisms of this cross-talk are often unclear. In regenerating Hydra …
systems, yet the mechanisms of this cross-talk are often unclear. In regenerating Hydra …