Systemic lupus erythematosus (SLE) is a chronic multi-organ debilitating autoimmune
disease, which mainly afflicts women in the reproductive years. A complex interaction of …

Juvenile-onset systemic lupus erythematosus (jSLE) accounts for up to 20% of all SLE
patients. Key differences between juvenile-and adult-onset (aSLE) disease include higher …

Lupus nephritis remains one of the most severe manifestations of systemic lupus
erythematosus associated with considerable morbidity and mortality. A better understanding …

Systemic lupus erythematosus (SLE) is a disease characterized by dysregulation and
hyperreactivity of the immune response at various levels, including hyperactivation of …

Background Juvenile-onset systemic lupus erythematosus (SLE) is a rare autoimmune
rheumatic disease characterised by more severe disease manifestations, earlier damage …

Studies on clinical features of systemic lupus erythematosus among different age-onset
patients are lacking in China. This multicentre study aimed to systemically compare clinical …

Objective To identify potential diagnostic markers of lupus nephritis (LN) based on
bioinformatics and machine learning and to explore the significance of immune cell …

An individual's immune function, susceptibility to infection, and response to
immunosuppressive therapy are influenced in part by his/her T cell maturation state …

Systemic lupus erythematosus (SLE) is a multiorgan autoimmune disease with increasing
mortality that often targets young women and children of United States minorities. Childhood …

Objective Juvenile-onset systemic lupus erythematosus (JSLE) is a complex and
heterogeneous immune-mediated disease. Cellular components have crucial roles in …