Neurotoxicity of pesticides

JR Richardson, V Fitsanakis, RHS Westerink… - Acta …, 2019 - Springer
Pesticides are unique environmental contaminants that are specifically introduced into the
environment to control pests, often by killing them. Although pesticide application serves …

Signal Transduction Associated with Mn-induced Neurological Dysfunction

X Zheng, Y Fang, J Lin, J Luo, S Li, M Aschner… - … Trace Element Research, 2024 - Springer
Manganese (Mn) is a heavy metal that occurs widely in nature and has a vital physiological
role in growth and development. However, excessive exposure to Mn can cause …

Acute mancozeb-fungicide exposure induces neuro-ethology disruption, health disorders, and immune-oxidative dysfunction in Nile tilapia (Oreochromis niloticus)

RE Ibrahim, MA Elbealy, GA Salem, AA Abdelwarith… - Aquatic Toxicology, 2023 - Elsevier
An acute exposure study of mancozeb (MAZ) fungicide was applied on Oreochromis
niloticus for 96-h duration. Three hundred fish (20.50±1.60 g) were assigned into six groups …

Neuroprotective effect of bromelain in 6-hydroxydopamine induced in vitro model of Parkinson's disease

I Ferah Okkay, U Okkay, B Cicek, A Yilmaz… - Molecular Biology …, 2021 - Springer
Background This study was designed to investigate the neuroprotective effects of bromelain,
which is known to have anti-oxidant and anti-inflammatory properties, against the …

Neurotoxicity assessment of triazole fungicides on mitochondrial oxidative respiration and lipids in differentiated human SH-SY5Y neuroblastoma cells

CL Sanchez, CL Souders II, CJ Pena-Delgado… - Neurotoxicology, 2020 - Elsevier
Indiscriminate overuse or occupational exposure to agricultural chemicals can lead to
neurotoxicity. Many pesticides act to impair mitochondrial function which can lead to …

Toxic effects of a mancozeb-containing commercial formulation at environmental relevant concentrations on zebrafish embryonic development

R Vieira, CAS Venâncio, LM Félix - Environmental Science and Pollution …, 2020 - Springer
The toxicological knowledge of mancozeb (MZ)-containing commercial formulations on non-
target species is scarce and limited. Therefore, the objective of this work was to represent a …

Behavioral changes occur earlier than redox alterations in develo** zebrafish exposed to Mancozeb

LP Leandro, RS de Mello, DG da Costa-Silva… - Environmental …, 2021 - Elsevier
As agriculture expands to provide food and wellbeing to the world's growing population,
there is a simultaneous increasing concern about the use of agrochemicals, which can harm …

Potential role of dietary Boswellia serrata resin against mancozeb fungicide-induced immune-antioxidant suppression, histopathological alterations, and genotoxicity …

ANA Rahman, DE Altohamy, GE Elshopakey… - Aquatic Toxicology, 2023 - Elsevier
This study was established to look into the toxicological consequences of chronic exposure
to a fungicide (mancozeb; MAZ) on the immune-antioxidant response, gene expressions …

The administration of Glycyrrhiza polysaccharides mitigates liver injury in mice caused by mancozeb via the Keap1-Nrf2/NF-κB pathway

N Gao, Y Li, L Zhang, Y Zhang, X Wang - Food and Chemical Toxicology, 2025 - Elsevier
The extensive utilization of mancozeb (MCZ) poses environmental pollution risks, threatens
human health, particularly hepatotoxicity. Glycyrrhiza polysaccharides (GP) exhibit …

[HTML][HTML] Fungal compound 1-octen-3-ol induces mitochondrial morphological alterations and respiration dysfunctions in Drosophila melanogaster

GE Macedo, P de Brum Vieira, NR Rodrigues… - Ecotoxicology and …, 2020 - Elsevier
Fungal volatile organic compounds (VOCs) comprise a group of compounds commonly
found in damp or water-damaged indoor places affecting air quality. Indoor fungal pollution …