[HTML][HTML] Platelet‐based coagulation: different populations, different functions
JWM Heemskerk, NJA Mattheij, J Cosemans - Journal of Thrombosis and …, 2013 - Elsevier
Platelets in a thrombus interact with (anti) coagulation factors and support blood
coagulation. In the concept of cell‐based control of coagulation, three different roles of …
coagulation. In the concept of cell‐based control of coagulation, three different roles of …
Mechanisms underlying dichotomous procoagulant COAT platelet generation—a conceptual review summarizing current knowledge
L Veuthey, A Aliotta, D Bertaggia Calderara… - International journal of …, 2022 - mdpi.com
Procoagulant platelets are a subtype of activated platelets that sustains thrombin generation
in order to consolidate the clot and stop bleeding. This aspect of platelet activation is gaining …
in order to consolidate the clot and stop bleeding. This aspect of platelet activation is gaining …
Transient receptor potential channels function as a coincidence signal detector mediating phosphatidylserine exposure
MT Harper, JEC Londoño, K Quick, JC Londoño… - Science …, 2013 - science.org
Blood platelet aggregation must be tightly controlled to promote clotting at injury sites but
avoid inappropriate occlusion of blood vessels. Thrombin, which cleaves and activates Gq …
avoid inappropriate occlusion of blood vessels. Thrombin, which cleaves and activates Gq …
Src-independent ERK signaling through the rat α3 isoform of Na/K-ATPase
The Na/K-ATPase α1 polypeptide supports both ion-pum** and signaling functions. The
Na/K-ATPase α3 polypeptide differs from α1 in both its primary structure and its tissue …
Na/K-ATPase α3 polypeptide differs from α1 in both its primary structure and its tissue …
Sodium–calcium exchanger reverse mode sustains dichotomous ion fluxes required for procoagulant COAT platelet formation
Procoagulant collagen-and-thrombin (COAT)-activated platelets represent a subpopulation
of activated platelets, which retain a coat of prohemostatic proteins and express …
of activated platelets, which retain a coat of prohemostatic proteins and express …
Polyhexamethylene Guanidine Phosphate Enhanced Procoagulant Activity through Oxidative-Stress-Mediated Phosphatidylserine Exposure in Platelets
JH Choi, K Kim - Toxics, 2024 - mdpi.com
Polyhexamethylene guanidine phosphate (PHMG-p) is a common biocidal disinfectant that
is widely used in industry and household products. However, PHMG-p was misused as a …
is widely used in industry and household products. However, PHMG-p was misused as a …
Flow cytometric monitoring of dynamic cytosolic calcium, sodium, and potassium fluxes following platelet activation
A Aliotta, D Bertaggia Calderara, L Alberio - Cytometry Part A, 2020 - Wiley Online Library
The interaction of platelet agonists with their respective membrane receptors triggers
intracellular signaling, among which cytosolic ion fluxes play an important role in activation …
intracellular signaling, among which cytosolic ion fluxes play an important role in activation …
The serum‐& glucocorticoid‐inducible kinase in the regulation of platelet function
F Lang, M Gawaz, O Borst - Acta physiologica, 2015 - Wiley Online Library
The serum‐and glucocorticoid‐inducible kinase 1 (SGK 1) is expressed in megakaryocytes
and circulating platelets. In megakaryocytes, SGK 1 activates transcription factor nuclear …
and circulating platelets. In megakaryocytes, SGK 1 activates transcription factor nuclear …
[HTML][HTML] The plasma membrane calcium ATPase modulates calcium homeostasis, intracellular signaling events and function in platelets
Background: The plasma membrane calcium ATPase (PMCA) regulates localized signaling
events in a variety of cell types, although its functional role in platelets remains undefined …
events in a variety of cell types, although its functional role in platelets remains undefined …
Involvement of hyperglycemia in the development of platelet procoagulant response: the role of aldose reductase and platelet swelling
T Rusak, T Misztal, M Rusak… - Blood Coagulation & …, 2017 - journals.lww.com
Rise in mean platelet volume (MPV) has been demonstrated to be associated with
increased platelet reactivity. In diabetes patients, augmented MPV was proposed to …
increased platelet reactivity. In diabetes patients, augmented MPV was proposed to …