A majority of industrial fermentation processes are operated in fed-batch mode. In this case,
the rate of feed addition to the system is a focus for optimising the process operation, as it …

We provide a systematic review of current progress in integrated control and operations.
Recently, an increasing number of integrated methods have been presented in the literature …

At publication, The Control Handbook immediately became the definitive resource that
engineers working with modern control systems required. Among its many accolades, that …

The dynamic optimization (open loop optimal control) of non-linear bioprocesses is
considered in this contribution. These processes can be described by sets of non-linear …

Industrial fermentation processes are increasingly popular, and are considered an important
technological asset for reducing our dependence on chemicals and products produced from …

We developed a dynamic flux balance model for fed‐batch Saccharomyces cerevisiae
fermentation that couples a detailed steady‐state description of primary carbon metabolism …

Dissolved oxygen plays a key role in microalgal growth at high density. This effect was so far
rarely quantified. Here we propose a new model to represent the combined effect of light …

Control technology permeates every aspect of our lives. We rely on them to perform a wide
variety of tasks without giving much thought to the origins of the technology or how it became …

Understanding the growth characteristics of microorganisms is an essential step in
bioprocessing, not only because product formation may be growth-associated but also …

Within this work a nonlinear model predictive controller (MPC) was implemented in a
Penicillium chrysogenum fed-batch process and compared to a PI (D) and an open loop …