Conspectus Indole alkaloids, one of the largest classes of alkaloids, serve as an important
and rich source of pharmaceuticals and have inspired synthetic chemists to develop novel …

By the end of the twentieth century, the interest in natural compounds as probable sources of
drugs has declined and was replaced by other strategies such as molecular target-based …

Nine new indole alkaloids, rhazinoline (1), 19 (S)-methoxytubotaiwine (2), 19 (R)-
methoxytubotaiwine (3), kopsamidine A (4), kopsamidine B (5), kopsinidine A (6) …

Due to their structural diversity, elegant polycyclic molecular architecture, and biological
activity, the indole alkaloids have been investigated by organic chemists over the last …

Kopsia belongs to the family Apocynaceae, which was originally classified as a genus in
1823. Kopsia consists of medicinal plants that can be traditionally used to treat rheumatoid …

Two novel indole alkaloids, alsmaphorazines A and B, were isolated from the leaves of
Alstonia pneumatophora (Apocynaceae), and their structures were determined on the basis …

Six new monoterpenoid indole alkaloids, kopsinidines C–E (1–3), 11, 12-
methylenedioxychanofruticosinic acid (4), 12-methoxychanofruticosinic acid (5), and N (4) …

The roots of the pharmaceutical industry can be traced to multiple sources, including
Perkins's dyeworks, Erlich's ideas of chemotherapy and the “magic bullet”, or the …

Natural product synthesis remains a field in which new synthetic methods and reagents are
continually being evaluated. Due to the demanding structures and complex functionality of …

Methyl N-decarbomethoxychanofruticosinate (1; Figure 1)[1] belongs to a growing family of
indole alkaloids with more than twenty members, namely methyl chanofruticosinates [2 …