Pain is common in cancer patients, particularly in the advanced stage of disease when the
prevalence is estimated to be more than 70%[1], contributing to poor physical and emotional …

The skeletal system is the third most common site for cancer metastases, surpassed only by
the lungs and liver. Many tumors, especially those of the breast, prostate, lungs, and …

There are three distinct areas of cancer management that make bone health in cancer
patients of increasing clinical importance. First, bone metastases are common in many solid …

According to a systematic review of the literature, pain prevalence ranges from 33% in
patients after curative treatment to 59% in patients on anticancer treatment and to 64% in …

As one of the most common metastatic sites of malignancies, bone has a unique
microenvironment that allows metastatic tumor cells to grow and flourish. The fenestrated …

Bone metastases, especially to the spine, are frequently encountered during the course of a
malignancy. Due to a worldwide increase of cancer incidence and to a longer life …

Metastatic bone disease in patients with advanced cancer is frequently associated with
skeletal complications. These can be debilitating, causing pain, impaired functioning and …

Abstract Background In Alpharadin in Symptomatic Prostate Cancer (ALSYMPCA) trial,
radium-223 versus placebo prolonged overall survival with favorable safety in castration …

Bone is a major site of haematogenous tumour cell spread in renal cell carcinoma (RCC),
and most patients with RCC will develop painful and functionally disabling bone metastases …

These guidelines cover a wide range of topics from prostate cancer epidemiology to
palliative care. Questions arising in daily clinical practice have been extracted and …