Drugs in development for toxoplasmosis: advances, challenges, and current status

PH Alday, JS Doggett - Drug design, development and therapy, 2017 - Taylor & Francis
Toxoplasma gondii causes fatal and debilitating brain and eye diseases. Medicines that are
currently used to treat toxoplasmosis commonly have toxic side effects and require …

OrthoMCL: identification of ortholog groups for eukaryotic genomes

L Li, CJ Stoeckert, DS Roos - Genome research, 2003 - genome.cshlp.org
The identification of orthologous groups is useful for genome annotation, studies on
gene/protein evolution, comparative genomics, and the identification of taxonomically …

Genome sequence of the human malaria parasite Plasmodium falciparum

MJ Gardner, N Hall, E Fung, O White, M Berriman… - Nature, 2002 - nature.com
The parasite Plasmodium falciparum is responsible for hundreds of millions of cases of
malaria, and kills more than one million African children annually. Here we report an …

Investigating deep phylogenetic relationships among cyanobacteria and plastids by small subunit rRNA sequence analysis 1

S Turner, KM Pryer, VPW Miao… - Journal of Eukaryotic …, 1999 - Wiley Online Library
Small subunit rRNA sequence data were generated for 27 strains of cyanobacteria and
incorporated into a phylogenetic analysis of 1,377 aligned sequence positions from a …

Thousands of chemical starting points for antimalarial lead identification

FJ Gamo, LM Sanz, J Vidal, C De Cozar, E Alvarez… - Nature, 2010 - nature.com
Malaria is a devastating infection caused by protozoa of the genus Plasmodium. Drug
resistance is widespread, no new chemical class of antimalarials has been introduced into …

Structures of Toxoplasma gondiiTachyzoites, Bradyzoites, and Sporozoites and Biology and Development of Tissue Cysts

JP Dubey, DS Lindsay, CA Speer - Clinical microbiology reviews, 1998 - Am Soc Microbiol
Infections by the protozoan parasite Toxoplasma gondii are widely prevalent worldwide in
animals and humans. This paper reviews the life cycle; the structure of tachyzoites …

[LIBRO][B] Life's solution: inevitable humans in a lonely universe

SC Morris - 2003 - books.google.com
The assassin's bullet misses, the Archduke's carriage moves forward, and a catastrophic war
is avoided. So too with the history of life. Re-run the tape of life, as Stephen J. Gould …