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Minor cannabinoids: Biosynthesis, molecular pharmacology and potential therapeutic uses
KB Walsh, AE McKinney, AE Holmes - Frontiers in pharmacology, 2021 - frontiersin.org
The medicinal use of Cannabis sativa L. can be traced back thousands of years to ancient
China and Egypt. While marijuana has recently shown promise in managing chronic pain …
China and Egypt. While marijuana has recently shown promise in managing chronic pain …
Cannabinoids as anticancer drugs: Current status of preclinical research
B Hinz, R Ramer - British journal of cancer, 2022 - nature.com
Drugs that target the endocannabinoid system are of interest as pharmacological options to
combat cancer and to improve the life quality of cancer patients. From this perspective …
combat cancer and to improve the life quality of cancer patients. From this perspective …
Medical cannabis activity against inflammation: active compounds and modes of action
Inflammation often develops from acute, chronic, or auto-inflammatory disorders that can
lead to compromised organ function. Cannabis (Cannabis sativa) has been used to treat …
lead to compromised organ function. Cannabis (Cannabis sativa) has been used to treat …
Anti-microbial activity of phytocannabinoids and endocannabinoids in the light of their physiological and pathophysiological roles
Antibiotic resistance has become an increasing challenge in the treatment of various
infectious diseases, especially those associated with biofilm formation on biotic and abiotic …
infectious diseases, especially those associated with biofilm formation on biotic and abiotic …
Effects of tetrahydrocannabinols on human oral cancer cell proliferation, apoptosis, autophagy, oxidative stress, and DNA damage
A Semlali, S Beji, I Ajala, M Rouabhia - Archives of Oral Biology, 2021 - Elsevier
Abstract Objective Cannabinoids, including delta-8-and delta-9-tetrahydrocannabinol (THC)
have a palliative care impact and may therefore be beneficial against cancer. The aim of this …
have a palliative care impact and may therefore be beneficial against cancer. The aim of this …
Cannabidiol in neurological and neoplastic diseases: Latest developments on the molecular mechanism of action
As the major nonpsychotropic constituent of Cannabis sativa, cannabidiol (CBD) is regarded
as one of the most promising therapeutic agents due to its proven effectiveness in clinical …
as one of the most promising therapeutic agents due to its proven effectiveness in clinical …
[HTML][HTML] Anti-Cancer Activity of Cannabis sativa Phytocannabinoids: Molecular Mechanisms and Potential in the Fight against Ovarian Cancer and Stem Cells
H Koltai, N Shalev - Cancers, 2022 - mdpi.com
Simple Summary Ovarian cancer is the most lethal gynecological malignancy. Cancer stem
cells have been implicated in tumor initiation, progression, and invasion, as well as tumor …
cells have been implicated in tumor initiation, progression, and invasion, as well as tumor …
Anti-cancer properties of cannflavin A and potential synergistic effects with gemcitabine, cisplatin, and cannabinoids in bladder cancer
AM Tomko, EG Whynot, DJ Dupré - Journal of Cannabis Research, 2022 - Springer
Introduction Several studies have shown anti-tumor effects of components present in
cannabis in different models. Unfortunately, little is known about the potential anti-tumoral …
cannabis in different models. Unfortunately, little is known about the potential anti-tumoral …
Cancer Initiation, Progression and Resistance: Are Phytocannabinoids from Cannabis sativa L. Promising Compounds?
Cannabis sativa L. is a source of over 150 active compounds known as phytocannabinoids
that are receiving renewed interest due to their diverse pharmacologic activities. Indeed …
that are receiving renewed interest due to their diverse pharmacologic activities. Indeed …
Cannabidiol and other phytocannabinoids as cancer therapeutics
G Nahler - Pharmaceutical medicine, 2022 - Springer
Preclinical models provided ample evidence that cannabinoids are cytotoxic against cancer
cells. Among the best studied phytocannabinoids, cannabidiol (CBD) is most promising for …
cells. Among the best studied phytocannabinoids, cannabidiol (CBD) is most promising for …