Melatonin—A pleiotropic, orchestrating regulator molecule
R Hardeland, DP Cardinali, V Srinivasan… - Progress in …, 2011 - Elsevier
Melatonin, the neurohormone of the pineal gland, is also produced by various other tissues
and cells. It acts via G protein-coupled receptors expressed in various areas of the central …
and cells. It acts via G protein-coupled receptors expressed in various areas of the central …
The role of melatonin in the cells of the innate immunity: a review
JR Calvo, C Gonzalez‐Yanes… - Journal of pineal …, 2013 - Wiley Online Library
Melatonin is the major secretory product synthesized and secreted by the pineal gland and
shows both a wide distribution within phylogenetically distant organisms from bacteria to …
shows both a wide distribution within phylogenetically distant organisms from bacteria to …
Melatonin in food allergy: Mechanism and potential therapy
H Wang, Y Yan, I Hung, C Liu, J Yin… - Journal of Pineal …, 2023 - Wiley Online Library
Food allergy affects more than 500 million people in the world, and its prevalence is
increasing at an alarming rate causing serious public health concerns; however, prevention …
increasing at an alarming rate causing serious public health concerns; however, prevention …
Melatonin signaling in T cells: Functions and applications
Melatonin affects a variety of physiological processes including circadian rhythms, cellular
redox status, and immune function. Importantly, melatonin significantly influences T‐cell …
redox status, and immune function. Importantly, melatonin significantly influences T‐cell …
Melatonin and the theories of aging: a critical appraisal of melatonin's role in antiaging mechanisms
R Hardeland - Journal of pineal research, 2013 - Wiley Online Library
The classic theories of aging such as the free radical theory, including its mitochondria‐
related versions, have largely focused on a few specific processes of senescence …
related versions, have largely focused on a few specific processes of senescence …
Melatonin mediates mucosal immune cells, microbial metabolism, and rhythm crosstalk: a therapeutic target to reduce intestinal inflammation
Nowadays, melatonin, previously considered only as a pharmaceutical product for rhythm
regulation and sleep aiding, has shown its potential as a co‐adjuvant treatment in intestinal …
regulation and sleep aiding, has shown its potential as a co‐adjuvant treatment in intestinal …
Melatonin, immune function and aging
Aging is associated with a decline in immune function (immunosenescence), a situation
known to correlate with increased incidence of cancer, infectious and degenerative …
known to correlate with increased incidence of cancer, infectious and degenerative …
The role of melatonin in immuno‐enhancement: potential application in cancer
SC Miller, PSR Pandi, AI Esquifino… - International journal …, 2006 - Wiley Online Library
Melatonin, a neurohormone produced mainly by the pineal gland, is a modulator of
haemopoiesis and of immune cell production and function, both in vivo and in vitro …
haemopoiesis and of immune cell production and function, both in vivo and in vitro …
Role of melatonin in the inflammatory process and its therapeutic potential
Melatonin is an indolamine synthesized and secreted by the pineal gland along with other
extrapineal sources including immune system cells, the brain, skin and the gastrointestinal …
extrapineal sources including immune system cells, the brain, skin and the gastrointestinal …
Cadmium activates the innate immune system through the AIM2 inflammasome
L Zhao, M Liao, L Li, L Chen, T Zhang, R Li - Chemico-Biological …, 2024 - Elsevier
Cadmium (Cd) is a widely used heavy metal and has recently been recognized as a
possible source of human toxicity due to its ability to accumulate in organs. Accumulation of …
possible source of human toxicity due to its ability to accumulate in organs. Accumulation of …