Alzheimer disease is a progressive neurodegenerative disorder, mainly affecting older
people, which severely impairs patients' quality of life. In the recent years, the number of …

Alzheimer's disease (AD) is a deadly brain degenerative disorder that leads to brain
shrinkage and dementia. AD is manifested with hyperphosphorylated tau protein levels and …

Finding an effective therapeutic to prevent or cure AD has been difficult due to the
complexity of the brain and limited experimental models. This study utilized unmodified and …

Alzheimer's disease (AD), the most prevalent, age-related, neurodegenerative disease, is
associated with the accumulation of amyloid beta (Aβ) and oxidative stress. However, the …

Alzheimer's disease (AD) is an incurable, age-related neurological disorder, the most
common form of dementia. Considering that AD is a multifactorial complex disease …

A large-scale epidemiology study on statins previously showed that simvastatin was unique
among statins in reducing the incidence of dementia. Since amyloid beta (Aβ42) is the …

Alzheimer's disease (AD) is an age-related, multifaceted neurological disorder associated
with accumulation of aggregated proteins (amyloid Aβ and hyperphosphorylated tau), loss of …

Yeast has been used as a model for several diseases as it is the simplest unicellular
eukaryote, safe and easy to culture and harbors most of the fundamental processes that are …

In this article, we briefly describe human neurodegenerative diseases (NDs) and the
experimental models used to study them. The main focus is the yeast Saccharomyces …

Abstract Alzheimer's disease (AD), the most common form of dementia, has gotten
considerable attention. Previous studies have demonstrated that clioquinol (CQ) as a metal …