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Undisclosed, unmet and neglected challenges in multi-omics studies
Multi-omics approaches have become a reality in both large genomics projects and small
laboratories. However, the multi-omics research community still faces a number of issues …
laboratories. However, the multi-omics research community still faces a number of issues …
Microalgal heterotrophic and mixotrophic culturing for bio-refining: from metabolic routes to techno-economics
In comparison with conventional photo-autotrophic cultivation, heterotrophic and mixotrophic
cultivations of microalgae offers a feasible strategy to produce biomass and valuable …
cultivations of microalgae offers a feasible strategy to produce biomass and valuable …
Pathway Tools version 13.0: integrated software for pathway/genome informatics and systems biology
Pathway Tools is a production-quality software environment for creating a type of model-
organism database called a Pathway/Genome Database (PGDB). A PGDB such as EcoCyc …
organism database called a Pathway/Genome Database (PGDB). A PGDB such as EcoCyc …
Environments that induce synthetic microbial ecosystems
Interactions between microbial species are sometimes mediated by the exchange of small
molecules, secreted by one species and metabolized by another. Both one-way …
molecules, secreted by one species and metabolized by another. Both one-way …
PaintOmics 4: new tools for the integrative analysis of multi-omics datasets supported by multiple pathway databases
PaintOmics is a web server for the integrative analysis and visualisation of multi-omics
datasets using biological pathway maps. PaintOmics 4 has several notable updates that …
datasets using biological pathway maps. PaintOmics 4 has several notable updates that …
[HTML][HTML] Multi-omics and metabolic modelling pipelines: challenges and tools for systems microbiology
Integrated-omics approaches are quickly spreading across microbiology research labs,
leading to (i) the possibility of detecting previously hidden features of microbial cells like …
leading to (i) the possibility of detecting previously hidden features of microbial cells like …
Metabolic network modeling of microbial interactions in natural and engineered environmental systems
We review approaches to characterize metabolic interactions within microbial communities
using Stoichiometric Metabolic Network (SMN) models for applications in environmental and …
using Stoichiometric Metabolic Network (SMN) models for applications in environmental and …
Metabolic engineering for enhancing microbial biosynthesis of advanced biofuels
Increasing global energy demand and environmental concerns associated with petroleum
have raised interest in biofuels for reducing dependency on crude oil and promote carbon …
have raised interest in biofuels for reducing dependency on crude oil and promote carbon …
The application of flux balance analysis in systems biology
An increasing number of genome‐scale reconstructions of intracellular biochemical
networks are being generated. Coupled with these stoichiometric models, several systems …
networks are being generated. Coupled with these stoichiometric models, several systems …
Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis
C Huthmacher, A Hoppe, S Bulik, HG Holzhütter - BMC systems biology, 2010 - Springer
Background Despite enormous efforts to combat malaria the disease still afflicts up to half a
billion people each year of which more than one million die. Currently no approved vaccine …
billion people each year of which more than one million die. Currently no approved vaccine …