Efficient access to chemical information contained in scientific literature, patents, technical
reports, or the web is a pressing need shared by researchers and patent attorneys from …

High-throughput technologies for DNA sequencing and for analyses of transcriptomes,
proteomes and metabolomes have provided the foundations for deciphering the structure …

Science, and the way we undertake research, is changing. The increasing rate of data
generation across all scientific disciplines is providing incredible opportunities for data …

Background Recently there has been an explosion of new data sources about genes,
proteins, genetic variations, chemical compounds, diseases and drugs. Integration of these …

Distributed systems are often modeled by objects that run concurrently, each with its own
processor, and communicate by synchronous remote method calls. This may be satisfactory …

New knowledge is produced at a continuously increasing speed, and the list of papers,
databases and other knowledge sources that a researcher in the life sciences needs to cope …

In the past 15 years, new “omics” technologies have made it possible to obtain high‐
resolution molecular snapshots of organisms, tissues, and even individual cells at various …

Background Life scientists need help in co** with the plethora of fast growing and
scattered knowledge resources. Ideally, this knowledge should be integrated in a form that …

Systems chemical biology, the integration of chemistry, biology and computation to generate
understanding about the way small molecules affect biological systems as a whole, as well …

Background Key to the success of e-Science is the ability to computationally evaluate expert-
composed hypotheses for validity against experimental data. Researchers face the …