The observation that heart failure with reduced ejection fraction is associated with elevated
circulating levels of pro-inflammatory cytokines opened a new area of research that has …

The identification of stem cells and growth factors as well as the development of biomaterials
hold great promise for regenerative medicine applications. However, the therapeutic efficacy …

Background Angiotensin converting enzyme 2 (ACE2), a monocarboxylase that degrades
angiotensin II to angiotensin 1–7, is also the functional receptor for severe acute respiratory …

Background—The pathophysiology of heart failure with normal ejection fraction (HFNEF) is
still under discussion. Here we report the influence of cardiac inflammation on extracellular …

Background—The role of adaptive immunity, especially CD4+ T-helper cells, has not yet
been systematically investigated in wound healing and remodeling after myocardial …

Background—Despite the emerging association between heart failure (HF) and
inflammation, the role of T cells, major players in chronic inflammation, has only recently …

Inflammation plays a major role in all phases of atherosclerosis. Stable plaques are
characterized by a chronic inflammatory infiltrate, whereas vulnerable and ruptured plaques …

Myocardial inflammation can lead to lethal acute or chronic heart failure (HF). T lymphocytes
(T cells), have been reported in the inflamed heart in different etiologies of HF, and more …

Heart failure (HF) has been traditionally viewed as a disease of the cardiac muscle
associated with systemic inflammation. Burgeoning evidence implicates immune effector …

Background—Lipoprotein-associated phospholipase A2 (Lp-PLA2) is associated with the
risk of cardiovascular (CV) events in population-based studies. The prognostic value of Lp …