The digital polymerase chain reaction (dPCR) is considered to be the third-generation
polymerase chain reaction (PCR), as it yields direct, absolute and precise measures of …

B cell lymphomas are heterogeneous malignancies of hematological origin with vastly
different biology and clinical outcomes. Histopathology of tissue biopsies and image-based …

Colorectal cancer (CRC) is the most common malignant tumor occurred in digestive system.
However, the prognosis of CRC patients is poor. Therefore, it is urgent to illuminate the …

We have identified and validated a spaceflight-associated microRNA (miRNA) signature that
is shared by rodents and humans in response to simulated, short-duration and long-duration …

In the last decades, emerging and reemerging infectious diseases marked the third
epidemiological transition (Figure 1A), characterized by:(i) identification of new emerging …

Spaceflight missions can cause immune system dysfunction in astronauts with little
understanding of immune outcomes in deep space. This study assessed immune responses …

Translating fundamental biological discoveries from NASA Space Biology program into
health risk from space flights has been an ongoing challenge. We propose to use NASA …

There remains a need to identify new sensitive diagnostic and predictive blood-based
platforms in lymphoma. We previously discovered a novel circulating microRNA (miRNA) …

Non-Hodgkin lymphoma (NHL) is a common type of hematological malignant tumor,
composed of multiple subtypes that originate from B lymphocytes, T lymphocytes, and …

Background Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous group of tumors,
with aggressive clinical course that renders prognostication and choice of treatment strategy …