Pathophysiology of sleep apnea

JA Dempsey, SC Veasey, BJ Morgan… - Physiological …, 2010 - journals.physiology.org
Sleep-induced apnea and disordered breathing refers to intermittent, cyclical cessations or
reductions of airflow, with or without obstructions of the upper airway (OSA). In the presence …

International consensus statement on obstructive sleep apnea

JL Chang, AN Goldberg, JA Alt… - International forum of …, 2023 - Wiley Online Library
Background Evaluation and interpretation of the literature on obstructive sleep apnea (OSA)
allows for consolidation and determination of the key factors important for clinical …

Effect of weight loss on upper airway anatomy and the apnea–hypopnea index. The importance of tongue fat

SH Wang, BT Keenan, A Wiemken, Y Zang… - American journal of …, 2020 - atsjournals.org
Rationale: Obesity is the primary risk factor for obstructive sleep apnea (OSA). Tongue fat is
increased in obese persons with OSA, and may explain the relationship between obesity …

Identification of upper airway anatomic risk factors for obstructive sleep apnea with volumetric magnetic resonance imaging

RJ Schwab, M Pasirstein, R Pierson… - American journal of …, 2003 - atsjournals.org
We used sophisticated volumetric analysis techniques with magnetic resonance imaging in
a case–control design to study the upper airway soft tissue structures in 48 control subjects …

Upper airway and soft tissue anatomy in normal subjects and patients with sleep-disordered breathing. Significance of the lateral pharyngeal walls.

RJ Schwab, KB Gupta, WB Gefter… - American journal of …, 1995 - atsjournals.org
The geometry and caliber of the upper airway in apneic patients differs from those in normal
subjects. The apneic airway is smaller and is narrowed laterally. Examination of the soft …

Obesity and obstructive sleep apnea: pathogenic mechanisms and therapeutic approaches

AR Schwartz, SP Patil, AM Laffan… - Proceedings of the …, 2008 - atsjournals.org
Obstructive sleep apnea is a common disorder whose prevalence is linked to an epidemic of
obesity in Western society. Sleep apnea is due to recurrent episodes of upper airway …

Pathogenesis of obstructive and central sleep apnea

DP White - American journal of respiratory and critical care …, 2005 - atsjournals.org
Considerable progress has been made over the last several decades in our understanding
of the pathophysiology of both central and obstructive sleep apnea. Central sleep apnea, in …

Pulmonary complications of obesity

SM Koenig - The American journal of the medical sciences, 2001 - Elsevier
Obesity can profoundly alter pulmonary function and diminish exercise capacity by its
adverse effects on respiratory mechanics, resistance within the respiratory system …

The male predisposition to pharyngeal collapse: importance of airway length

A Malhotra, Y Huang, RB Fogel, G Pillar… - American journal of …, 2002 - atsjournals.org
Obstructive sleep apnea is an important disorder because of both its prevalence and its
cardiovascular and neurocognitive sequelae. Despite the fact that male sex is a major risk …

Obstructive sleep apnea

SM Caples, AS Gami, VK Somers - Annals of internal medicine, 2005 - acpjournals.org
Obstructive sleep apnea remains an important public health problem because of its
neurocognitive sequelae. This review covers the epidemiology, clinical presentation, and …