Shared genetic risk across different presentations of gene test–negative idiopathic nephrotic syndrome

ML Downie, S Gupta, MMY Chan… - Pediatric …, 2023 - Springer
Background Idiop athic nephrotic syndrome (INS) is classified in children according to
response to initial corticosteroid therapy into steroid-sensitive (SSNS) and steroid-resistant …

[HTML][HTML] A Genetic Risk Score Distinguishes Different Types of Autoantibody-Mediated Membranous Nephropathy

S Gupta, ML Downie, C Cheshire… - Glomerular …, 2023 - karger.com
Introduction: Membranous nephropathy (MN) is the leading cause of nephrotic syndrome in
adults and is characterized by detectable autoantibodies against glomerular antigens, most …

Association between PLA2R gene polymorphism and idiopathic membranous nephropathy in Heilongjiang Chinese

T Tian, J Zheng, Y Li, Q Guo… - Annals of Translational …, 2023 - pmc.ncbi.nlm.nih.gov
Background The aim of this study was to investigate the correlation between the
phospholipase A2 receptor (PLA2R) gene polymorphism and idiopathic membranous …

Using genetics to understand childhood nephrotic syndromes

ML Downie - 2022 - discovery.ucl.ac.uk
Idiopathic nephrotic syndrome (INS) is classified in children according to response to initial
corticosteroid therapy into steroid sensitive (SSNS) and steroid resistant nephrotic syndrome …

[HTML][HTML] Membranous pathogenesis–Manchester

R Bright - ukkidneyhistory.org
Membranous nephropathy is a type of glomerulonephritis in which autoantibodies to an
antigen on the surface of the podocyte lead to severe nephrotic syndrome, and often …

[SITAATTI][C] A Genetic Risk Score Distinguishes Different Types of Autoantibody-Mediated Membranous Nephropathy

SDKAP Levinea, P Brenchleyb, E Hoxhac… - 2023