Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery
and have found clinical use. Hydrogels can provide spatial and temporal control over the …

Biological barriers to drug transport prevent successful accumulation of nanotherapeutics
specifically at diseased sites, limiting efficacious responses in disease processes ranging …

Hydrogel microparticles (HMPs) are promising for biomedical applications, ranging from the
therapeutic delivery of cells and drugs to the production of scaffolds for tissue repair and …

The impact of physical and chemical modifications of nanoparticles on their biological
function has been systemically investigated and exploited to improve their circulation and …

Nature employs a variety of tactics to precisely time and execute the processes and
mechanics of life, relying on sequential sense and response cascades to transduce …

Red blood cells (RBCs) constitute a unique drug delivery system as a biologic or hybrid
carrier capable of greatly enhancing pharmacokinetics, altering pharmacodynamics (for …

Modulating nanomedicine mechanical properties for enhanced drug delivery to tumors has
attracted increasing attention in the past few decades. In this tutorial review, we analyze the …

Injectable biomaterials provide the advantage of a minimally invasive application but mostly
lack the required structural complexity to regenerate aligned tissues. Here, we report a new …

Research into long-circulating nanoparticles has in the past focused on reducing their
clearance by macrophages. By engineering a hierarchical polyethylene glycol (PEG) …

RNA nanotechnology is the bottom-up self-assembly of nanometer-scale architectures,
resembling LEGOs, composed mainly of RNA. The ideal building material should be (1) …