Muscle fatigue is an exercise-induced reduction in maximal voluntary muscle force. It may
arise not only because of peripheral changes at the level of the muscle, but also because …

The microorganisms in the gastrointestinal tract play a significant role in nutrient uptake,
vitamin synthesis, energy harvest, inflammatory modulation, and host immune response …

Background Changes in diet and exercise can alter the gut microbiome of humans and
mice; however, few studies to date have assessed the microbiomes of highly fit athletes. In …

The leading textbook for undergraduate exercise physiology courses, Physiology of Sport
and Exercise, is back in an updated fourth edition that is better than ever after extensive …

Brain serotonin and dopamine are neurotransmitters related to fatigue, a feeling that leads to
reduced intensity or interruption of physical exercises, thereby regulating performance. The …

Physical exercise influences the central dopaminergic, noradrenergic and serotonergic
systems. A number of studies have examined brain noradrenaline (norepinephrine) …

OBJECTIVES: This review aims to define the concept of neuromuscular fatigue and to
present the current knowledge of the central and peripheral factors at the origin of this …

Cancer-related fatigue (CRF) is one of the most prevalent symptoms patients with cancer
experience, both during and after treatment. CRF is pervasive and affects patients' quality of …

The original central fatigue hypothesis suggested that an exercise-induced increase in
extracellular serotonin concentrations in several brain regions contributed to the …

Branched-chain amino acids (BCAAs) influence brain function by modifying large, neutral
amino acid (LNAA) transport at the blood–brain barrier. Transport is shared by several …