An ancient conflict between hosts and pathogens has driven the innate and adaptive arms of
immunity. Knowledge about this interplay can not only help us identify biological …

ADAR deaminases catalyze adenosine‐to‐inosine (A‐to‐I) editing on double‐stranded RNA
(dsRNA) substrates that regulate an umbrella of biological processes. One of the two …

Viruses rely on hosts for life and reproduction, cause a variety of symptoms from common
cold to AIDS to COVID-19 and provoke public health threats claiming millions of lives around …

The post-transcriptional RNA modifications impact the dynamic regulation of gene
expression in diverse biological and physiological processes. Host RNA modifications play …

The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) induced coronavirus
disease 2019 (COVID-19) has recently caused a pandemic. Patients with COVID-19 …

Abstract Nonstructural protein 5 (Nsp5) is the main protease of SARS-CoV-2 that cleaves
viral polyproteins into individual polypeptides necessary for viral replication. Here, we show …

Ophthalmic manifestations have recently been observed in acute and post-acute
complications of COVID-19 caused by SARS-CoV-2 infection. Our precious study has shown …

Adenosine to inosine (A-to-I) RNA editing by ADAR1 has been implicated in maintaining self-
tolerance, preventing autoimmunity, and mediating antiviral immunity. Foreign viral double …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent
of COVID-19 and responsible for the global coronavirus pandemic which started in 2019 …

Background COVID-19 vaccines are crucial for reducing the threat and burden of the
pandemic on global public health, yet the epigenetic, especially RNA editing in response to …