Crystal engineering of pharmaceutical cocrystals in the discovery and development of improved drugs
The subject of crystal engineering started in the 1970s with the study of topochemical
reactions in the solid state. A broad chemical definition of crystal engineering was published …
reactions in the solid state. A broad chemical definition of crystal engineering was published …
Drug delivery by supramolecular design
The rational design of drug delivery approaches leveraging supramolecular chemistry
(ie,“chemistry beyond the molecule”) has garnered significant interest in recent years toward …
(ie,“chemistry beyond the molecule”) has garnered significant interest in recent years toward …
Supramolecular materials
Molecular material properties depend upon the contacts between and the arrangement of
the component parts, and therefore supramolecular chemistry has developed a highly …
the component parts, and therefore supramolecular chemistry has developed a highly …
Open questions in organic crystal polymorphism
AJ Cruz-Cabeza, N Feeder, RJ Davey - Communications Chemistry, 2020 - nature.com
Polymorphs, crystals with different structure and properties but the same molecular
composition, arise from the subtle interplay between thermodynamics and kinetics during …
composition, arise from the subtle interplay between thermodynamics and kinetics during …
[HTML][HTML] Encapsulated nanodroplet crystallization of organic-soluble small molecules
Single-crystal X-ray diffraction analysis (SCXRD) constitutes a universal approach for the
elucidation of molecular structure and the study of crystalline forms. However, the discovery …
elucidation of molecular structure and the study of crystalline forms. However, the discovery …
Supramolecular chemistry: a toolkit for soft functional materials and organic particles
Self-assembly has proven to be a powerful tool for the construction of complex
superstructures. The assembly of monomers into supramolecular architectures via non …
superstructures. The assembly of monomers into supramolecular architectures via non …
Modular, multi-robot integration of laboratories: an autonomous workflow for solid-state chemistry
Automation can transform productivity in research activities that use liquid handling, such as
organic synthesis, but it has made less impact in materials laboratories, which require …
organic synthesis, but it has made less impact in materials laboratories, which require …
Polymorph‐Dependent Thermally Activated Delayed Fluorescence Emitters: Understanding TADF from a Perspective of Aggregation State
Current research on thermally activated fluorescence (TADF) emitters is mainly based on the
molecular levels, while the aggregation states of TADF emitters are to be explored deeply …
molecular levels, while the aggregation states of TADF emitters are to be explored deeply …
Peptide-Based Gel in Environmental Remediation: Removal of Toxic Organic Dyes and Hazardous Pb2+ and Cd2+ Ions from Wastewater and Oil Spill Recovery
A dipeptide-based synthetic amphiphile bearing a myristyl chain has been found to form
hydrogels in the pH range 6.9–8.5 and organogels in various organic solvents including …
hydrogels in the pH range 6.9–8.5 and organogels in various organic solvents including …
Supramolecular gels: a versatile crystallization toolbox
Supramolecular gels are unique materials formed through the self-assembly of molecular
building blocks, typically low molecular weight gelators (LMWGs), driven by non-covalent …
building blocks, typically low molecular weight gelators (LMWGs), driven by non-covalent …