[HTML][HTML] Measuring and using light in the melanopsin age

RJ Lucas, SN Peirson, DM Berson, TM Brown… - Trends in …, 2014 - cell.com
Light is a potent stimulus for regulating circadian, hormonal, and behavioral systems. In
addition, light therapy is effective for certain affective disorders, sleep problems, and …

Melanopsin and the intrinsically photosensitive retinal ganglion cells: biophysics to behavior

MTH Do - Neuron, 2019 - cell.com
The mammalian visual system encodes information over a remarkable breadth of
spatiotemporal scales and light intensities. This performance originates with its complement …

Circadian photoentrainment in mice and humans

RG Foster, S Hughes, SN Peirson - Biology, 2020 - mdpi.com
Light around twilight provides the primary entrainment signal for circadian rhythms. Here we
review the mechanisms and responses of the mouse and human circadian systems to light …

Intrinsically photosensitive retinal ganglion cells

MTH Do, KW Yau - Physiological reviews, 2010 - journals.physiology.org
Life on earth is subject to alternating cycles of day and night imposed by the rotation of the
earth. Consequently, living things have evolved photodetective systems to synchronize their …

Spectral responses of the human circadian system depend on the irradiance and duration of exposure to light

JJ Gooley, SMW Rajaratnam, GC Brainard… - Science translational …, 2010 - science.org
In humans, modulation of circadian rhythms by light is thought to be mediated primarily by
melanopsin-containing retinal ganglion cells, not rods or cones. Melanopsin cells are …

[BOOK][B] Chronotherapeutics for Affective Disorders: A Clinician's Manual for Light and Wake Therapy, 2nd

A Wirz-Justice, F Benedetti, M Terman - 2013 - books.google.com
Light therapy'is established worldwide as the treatment of choice for seasonal affective
disorder. It is also successfuly used in nonseasonal depression, as well as for many other …

[HTML][HTML] The influence of intrinsically-photosensitive retinal ganglion cells on the spectral sensitivity and response dynamics of the human pupillary light reflex

DH McDougal, PD Gamlin - Vision research, 2010 - Elsevier
Historically, it was assumed that the light-evoked neural signals driving the human pupillary
light reflex (PLR) originated exclusively from rod and cone photoreceptors. However, a novel …

Melanopsin regulates both sleep-promoting and arousal-promoting responses to light

V Pilorz, SKE Tam, S Hughes, CA Pothecary… - PLoS …, 2016 - journals.plos.org
Light plays a critical role in the regulation of numerous aspects of physiology and behaviour,
including the entrainment of circadian rhythms and the regulation of sleep. These responses …

Sensitivity of the human circadian system to short-wavelength (420-nm) light

GC Brainard, D Sliney, JP Hanifin… - Journal of biological …, 2008 - journals.sagepub.com
The circadian and neurobehavioral effects of light are primarily mediated by a retinal
ganglion cell photoreceptor in the mammalian eye containing the photopigment melanopsin …

[HTML][HTML] Toward a clinical protocol for assessing rod, cone, and melanopsin contributions to the human pupil response

JC Park, AL Moura, AS Raza, DW Rhee… - … & visual science, 2011 - jov.arvojournals.org
Purpose.: To better understand the relative contributions of rod, cone, and melanopsin to the
human pupillary light reflex (PLR) and to determine the optimal conditions for assessing the …