Gamma-aminobutyric acid (GABA) is a non-protein amino acid widely distributed in nature
and extensively explored for its numerous physiological functions and effects on metabolic …

Unnatural amino acid (UAA) incorporation by amber codon suppression offers scientists a
powerful tool to modify the properties of proteins at will. UAA incorporation has been used …

Endotoxins are the major contributors to the pyrogenic response caused by contaminated
pharmaceutical products, formulation ingredients, and medical devices. Recombinant …

Advances in fermentation technologies have resulted in the production of increased yields of
proteins of economic, biopharmaceutical, and medicinal importance. Consequently, there is …

Nutraceutical compounds as plant flavonoids play an important role in prevention and
modulation of diverse heath conditions, as they exert interesting antifungal, antibacterial …

Scope Investigations into the immunological response of proteins is often masked by
lipopolysaccharide (LPS) contamination. We report an optimized Triton X-114 (TX-114) …

Approximately one third of protein therapeutics are produced in Escherichia coli, targeting a
wide variety of diseases. However, due to immune recognition of endotoxin (a lipid …

Our environment poses a constant threat to our health. To survive, all organisms must be
able to discriminate between good (food ingredients and microbes that help digest our food) …

Bacterial virus use as antibacterial agents, in the guise of what is commonly known as
phage therapy, is an inherently physiological, ecological, and also pharmacological …

Escherichia coli still serves as a beloved workhorse for the production of many
biopharmaceuticals as it fulfills essential criteria, such as having fast doubling times …