Experimental animal models for COPD: a methodological review
Introduction Chronic obstructive pulmonary disease (COPD) is a progressive disorder that
makes the breathing difficult and is characterized by pathological conditions ranging from …
makes the breathing difficult and is characterized by pathological conditions ranging from …
Chronic obstructive pulmonary disease and atherosclerosis: common mechanisms and novel therapeutics
Chronic obstructive pulmonary disease (COPD) and atherosclerosis are chronic irreversible
diseases, that share a number of common causative factors including cigarette smoking …
diseases, that share a number of common causative factors including cigarette smoking …
Necroptosis signaling promotes inflammation, airway remodeling, and emphysema in chronic obstructive pulmonary disease
Z Lu, HP Van Eeckhoutte, G Liu, PM Nair… - American journal of …, 2021 - atsjournals.org
Rationale: Necroptosis, mediated by RIPK3 (receptor-interacting protein kinase 3) and
MLKL (mixed lineage kinase domain-like), is a form of regulated necrosis that can drive …
MLKL (mixed lineage kinase domain-like), is a form of regulated necrosis that can drive …
[HTML][HTML] Matched-comparative modeling of normal and diseased human airway responses using a microengineered breathing lung chip
Smoking represents a major risk factor for chronic obstructive pulmonary disease (COPD),
but it is difficult to characterize smoke-induced injury responses under physiological …
but it is difficult to characterize smoke-induced injury responses under physiological …
COPD and stroke: are systemic inflammation and oxidative stress the missing links?
Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow
limitation and loss of lung function, and is currently the third largest cause of death in the …
limitation and loss of lung function, and is currently the third largest cause of death in the …
Mechanisms, pathophysiology and currently proposed treatments of chronic obstructive pulmonary disease
SO Rodrigues, CMC Cunha, GMV Soares, PL Silva… - Pharmaceuticals, 2021 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is one of the leading global causes of
morbidity and mortality. A hallmark of COPD is progressive airflow obstruction primarily …
morbidity and mortality. A hallmark of COPD is progressive airflow obstruction primarily …
[HTML][HTML] Novel insights into ferroptosis: Implications for age-related diseases
RP Zhou, Y Chen, X Wei, B Yu, ZG **ong, C Lu… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rapid increase in aging populations is an urgent problem because older adults are more
likely to suffer from disabilities and age-related diseases (ARDs), burdening healthcare …
likely to suffer from disabilities and age-related diseases (ARDs), burdening healthcare …
Senescent cells: SASPected drivers of age-related pathologies
The progression of physiological ageing is driven by intracellular aberrations including
telomere attrition, genomic instability, epigenetic alterations and loss of proteostasis. These …
telomere attrition, genomic instability, epigenetic alterations and loss of proteostasis. These …
Aspergillus fumigatus and aspergillosis: From basics to clinics
The airborne fungus Aspergillus fumigatus poses a serious health threat to humans by
causing numerous invasive infections and a notable mortality in humans, especially in …
causing numerous invasive infections and a notable mortality in humans, especially in …
Animal models of chronic obstructive pulmonary disease
Introduction: Chronic obstructive pulmonary disease (COPD) is a leading global cause of
mortality and chronic morbidity. Inhalation of cigarette smoke is the principal risk factor for …
mortality and chronic morbidity. Inhalation of cigarette smoke is the principal risk factor for …