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Glycoproteomics
Protein glycosylation involves the co-translational or post-translational addition of glycans to
proteins and is a crucial protein modification in health and disease. The aim of …
proteins and is a crucial protein modification in health and disease. The aim of …
[HTML][HTML] A pragmatic guide to enrichment strategies for mass spectrometry–based glycoproteomics
Glycosylation is a prevalent, yet heterogeneous modification with a broad range of
implications in molecular biology. This heterogeneity precludes enrichment strategies that …
implications in molecular biology. This heterogeneity precludes enrichment strategies that …
Chemical glycoproteomics
Chemical tools have accelerated progress in glycoscience, reducing experimental barriers
to studying protein glycosylation, the most widespread and complex form of posttranslational …
to studying protein glycosylation, the most widespread and complex form of posttranslational …
Mammalian brain glycoproteins exhibit diminished glycan complexity compared to other tissues
Glycosylation is essential to brain development and function, but prior studies have often
been limited to a single analytical technique and excluded region-and sex-specific analyses …
been limited to a single analytical technique and excluded region-and sex-specific analyses …
The challenge and promise of glycomics
RD Cummings, JM Pierce - Chemistry & biology, 2014 - cell.com
Glycomics is a broad and emerging scientific discipline focused on defining the structures
and functional roles of glycans in biological systems. The staggering complexity of the …
and functional roles of glycans in biological systems. The staggering complexity of the …
Oligosaccharide synthesis and translational innovation
The translation of biological glycosylation in humans to the clinical applications involves
systematic studies using homogeneous samples of oligosaccharides and glycoconjugates …
systematic studies using homogeneous samples of oligosaccharides and glycoconjugates …
Recent advances in glycoproteomic analysis by mass spectrometry
Glycosylation is one of the most common protein modifications and is essential for cells. This
modification is exceptionally complex because glycans are highly diverse and can be …
modification is exceptionally complex because glycans are highly diverse and can be …
Structural basis of adhesive binding by desmocollins and desmogleins
Desmosomes are intercellular adhesive junctions that impart strength to vertebrate tissues.
Their dense, ordered intercellular attachments are formed by desmogleins (Dsgs) and …
Their dense, ordered intercellular attachments are formed by desmogleins (Dsgs) and …
Mannose metabolism: more than meets the eye
Mannose is a simple sugar with a complex life. It is a welcome therapy for genetic and
acquired human diseases, but it kills honeybees and blinds baby mice. It could cause …
acquired human diseases, but it kills honeybees and blinds baby mice. It could cause …
Neurological aspects of human glycosylation disorders
HH Freeze, EA Eklund, BG Ng… - Annual review of …, 2015 - annualreviews.org
This review presents principles of glycosylation, describes the relevant glycosylation
pathways and their related disorders, and highlights some of the neurological aspects and …
pathways and their related disorders, and highlights some of the neurological aspects and …