Inhibiting extracellular vesicles formation and release: a review of EV inhibitors
M Catalano, L O'Driscoll - Journal of extracellular vesicles, 2020 - Taylor & Francis
It is now becoming well established that vesicles are released from a broad range of cell
types and are involved in cell-to-cell communication, both in physiological and pathological …
types and are involved in cell-to-cell communication, both in physiological and pathological …
Extracellular vesicles and particles impact the systemic landscape of cancer
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …
A comparison of methods for the isolation and separation of extracellular vesicles from protein and lipid particles in human serum
K Brennan, K Martin, SP FitzGerald, J O'sullivan… - Scientific reports, 2020 - nature.com
Extracellular vesicles (EVs) are nano-sized vesicles containing nucleic acid and protein
cargo that are released from a multitude of cell types and have gained significant interest as …
cargo that are released from a multitude of cell types and have gained significant interest as …
Exosomal cargos-mediated metabolic reprogramming in tumor microenvironment
S Tan, Y Yang, W Yang, Y Han, L Huang… - Journal of Experimental …, 2023 - Springer
Metabolic reprogramming is one of the hallmarks of cancer. As nutrients are scarce in the
tumor microenvironment (TME), tumor cells adopt multiple metabolic adaptations to meet …
tumor microenvironment (TME), tumor cells adopt multiple metabolic adaptations to meet …
Tumor-derived exosomes in the regulation of macrophage polarization
Background This review focuses on exosomes derived from various cancer cells. The review
discusses the possibility of differentiating macrophages in alternatively activated anti …
discusses the possibility of differentiating macrophages in alternatively activated anti …
Scalable production of human mesenchymal stromal cell-derived extracellular vesicles under serum-/xeno-free conditions in a microcarrier-based bioreactor culture …
Mesenchymal stromal cells (MSC) hold great promise for tissue engineering and cell-based
therapies due to their multilineage differentiation potential and intrinsic immunomodulatory …
therapies due to their multilineage differentiation potential and intrinsic immunomodulatory …
Hypoxia-driven effects in cancer: characterization, mechanisms, and therapeutic implications
Hypoxia, a common feature of solid tumors, greatly hinders the efficacy of conventional
cancer treatments such as chemo-, radio-, and immunotherapy. The depletion of oxygen in …
cancer treatments such as chemo-, radio-, and immunotherapy. The depletion of oxygen in …
Hypoxia in tumor microenvironment regulates exosome biogenesis: Molecular mechanisms and translational opportunities
Hypoxia is a key feature of solid tumors, associated with disease aggressiveness and poor
outcome. Besides undergoing broad intracellular molecular and metabolic adaptations …
outcome. Besides undergoing broad intracellular molecular and metabolic adaptations …
Milk-derived extracellular vesicles in inter-organism, cross-species communication and drug delivery
Milk is considered as more than a source of nutrition for infants and is a vector involved in
the transfer of bioactive compounds and cells. Milk contains abundant quantities of …
the transfer of bioactive compounds and cells. Milk contains abundant quantities of …
Dissecting exosome inhibitors: therapeutic insights into small-molecule chemicals against cancer
JH Kim, CH Lee, MC Baek - Experimental & Molecular Medicine, 2022 - nature.com
Intensive research in the field of cancer biology has revealed unique methods of
communication between cells through extracellular vesicles called exosomes. Exosomes …
communication between cells through extracellular vesicles called exosomes. Exosomes …