Taurine, a naturally occurring sulfur-containing amino acid, has attracted significant attention
in recent years due to its potential health benefits. Found in various foods and often used in …

The hallmarks of aging constitute an interconnected network of basic mechanisms that
modulate aging and can be modulated by lifestyle factors, including dietary strategies. This …

Nutrient sensing pathways influence metabolic health and aging, offering the possibility that
diet might be used therapeutically, alone or with drugs targeting these pathways. We used …

Rodents have been the primary model for mammalian nutritional physiology for decades.
Despite an extensive body of literature, controversies remain around the effects of specific …

Nutrition profoundly influences the risk for many age‐related diseases. Whether nutrition
influences human aging biology directly is less clear. Studies in different animal species …

Carbohydrates are the major source of dietary energy, but their role in health and disease
remains controversial. Recent epidemiological evidence suggests that the increased …

Aging affects the structure and function of the liver. Hydroxysafflor yellow A (HSYA)
effectively improves liver aging (LA) in mice, but the potential mechanisms require further …

Over the past decade, extensive efforts have focused on understanding age-associated
diseases and how to prolong a healthy lifespan. The induction of dietary protocols such as …

Background & aims The effect of dietary macronutrient balance on longevity and metabolic
health remains a subject of considerable interest. We aimed to investigate the association of …

The beneficial longevity effect of a simple reduction in calorie intake was first established in
rodent studies more than 80 years ago (1). In the interim, the caloric restriction (CR) …