Cell migration is essential for a wide range of biological processes such as embryo
morphogenesis, wound healing, regeneration, and also in pathological conditions, such as …

Physical properties of tissue are increasingly recognised as major regulatory cues affecting
cell behaviours, particularly cell migration. While these properties of the extracellular matrix …

The nervous system is shielded from circulating immune cells by the blood-brain barrier
(BBB). During infections and autoimmune diseases, macrophages can enter the brain where …

Cells migrate through crowded microenvironments within tissues during normal
development, immune response, and cancer metastasis. Although migration through pores …

Recognizing the crucial role of mechanical regulation and forces in tissue development and
homeostasis has stirred a demand for in situ measurement of forces and stresses. Among …

The infiltration of immune cells into tissues underlies the establishment of tissue-resident
macrophages and responses to infections and tumors. Yet the mechanisms immune cells …

The process by which biological systems such as cells, tissues and organisms acquire
shape has been named as morphogenesis and it is central to a plethora of biological …

The conserved multiple PDZ-domain containing protein PATJ stabilizes the Crumbs-Pals1
complex to regulate apical-basal polarity and tight junction formation in epithelial cells …

During embryogenesis, tissues develop into elaborate collectives through a myriad of active
mechanisms, with cell migration being one of the most common. As cells migrate, they …

Cellular metabolism must adapt to changing demands to enable homeostasis. During
immune responses or cancer metastasis, cells leading migration into challenging …