Amorphous solid dispersion (ASD) is one of the most effective approaches for delivering
poorly soluble drugs. In ASDs, polymeric materials serve as the carriers in which the drugs …

In recent years, the coamorphous drug delivery system has been established as a promising
formulation approach for delivering poorly water-soluble drugs. The coamorphous solid is a …

Drug polymorphism, an established term used to describe the phenomenon that a drug can
exist in different crystalline phases, has attracted great interests in pharmaceutical field in …

Amorphous solid dispersions stabilized by one or more polymer (s) have been widely used
for delivering amorphous drugs with poor water solubilities, and they have gained great …

Amorphous solid dispersions (ASDs) are a formulation and development strategy that can
be used to increase the apparent aqueous solubility of poorly water-soluble drugs. Their …

Molecular interactions between the active pharmaceutical ingredient and polymer have
potentially substantial impacts on the physical stability of amorphous solid dispersions …

Compared to their crystalline forms, amorphous pharmaceutical solids present marvelous
potential and advantages for effectively improving the oral bioavailability of poorly water …

In the recent years, coamorphous systems, containing an active pharmaceutical ingredient
(API) and a small molecule coformer have appeared as alternatives to the use of either …

Coamorphous and cocrystal drug delivery systems provide attractive crystal engineering
strategies for improving the solubilities, dissolution rates, and oral bioavailabilities of poorly …

A thorough understanding of effects of polymers on crystallization of amorphous drugs is
essential for rational design of robust amorphous solid dispersion (ASD), since …