Multiple roles of reactive oxygen species (ROS) and their consequences for health and
disease are emerging throughout biological sciences. This development has led …

Reactive oxygen species and reactive nitrogen species are biological molecules that play
important roles in cardiovascular physiology and contribute to disease initiation …

Reactive oxygen species (ROS) play a crucial role in physiological and pathological
processes, emerging as a therapeutic target in cancer. Owing to the high concentration of …

Significance: Mitochondrial and cellular reactive oxygen species (ROS) play important roles
in both physiological and pathological processes. Different ROS, such as superoxide (O2•−) …

The mechanism of superoxide generation by endothelial nitric oxide synthase (eNOS) was
investigated by the electron spin resonance spin-trap** technique using 5 …

Chemical probes for free radicals in biology are important tools; fluorescence and
chemiluminescence offer high detection sensitivity. This article reviews progress in the …

Hydroethidine (HE; or dihydroethidium) is the most popular fluorogenic probe used for
detecting intracellular superoxide radical anion. The reaction between superoxide and HE …

Facile detection of reactive oxygen and nitrogen species in biologic systems is often
problematic. This is a result of the numerous cellular mechanisms, both enzymatic and …

The importance of reactive oxygen species (ROS) in vascular physiology and pathology is
becoming increasingly evident. All cell types in the vascular wall produce ROS derived from …

A large body of literature suggest that vascular reduced nicotinamide-adenine dinucleotide
phosphate (NADPH) oxidases are important sources of reactive oxygen species. Many …