Many thousands of lipid species exist and their metabolism is interwoven via numerous
pathways and networks. These networks can also change in response to cellular …

The general secretory (Sec) pathway comprises an essential, ubiquitous and universal
export machinery for most proteins that integrate into, or translocate through, the plasma …

Phosphatidylethanolamine (PE) is the second most abundant glycerophospholipid in
eukaryotic cells. The existence of four only partially redundant biochemical pathways that …

Advances over the past 25 years have revealed much about how the structural properties of
membranes and associated proteins are linked to the thermodynamics and kinetics of …

Bacteria have evolved multiple strategies to sense and rapidly adapt to challenging and
ever-changing environmental conditions. The ability to alter membrane lipid composition, a …

Publisher Summary A primary role of lipids in cellular function is in the formation of the
permeability barrier of cells and subcellular organelles in the form of a lipid bilayer. This …

Extracellular vesicles (EVs) are important mediators of intercellular communication that
change the recipient cell by shuttling lipids, RNA, or protein cargo between cells. Here, we …

Microorganisms typically used to produce food and pharmaceuticals are now being
explored as medicines and agricultural supplements. However, maintaining high viability …

Membrane proteins interact with a myriad of lipid species in the biological membrane,
leading to a bewildering number of possible protein− lipid assemblies. Despite this inherent …

Cardiolipin (CL) is a unique phospholipid with a dimeric structure having four acyl chains
and two phosphate groups found almost exclusively in certain membranes of bacteria and of …