Mechanistic pathways of sex differences in cardiovascular disease
V Regitz-Zagrosek, G Kararigas - Physiological reviews, 2017 - journals.physiology.org
Major differences between men and women exist in epidemiology, manifestation,
pathophysiology, treatment, and outcome of cardiovascular diseases (CVD), such as …
pathophysiology, treatment, and outcome of cardiovascular diseases (CVD), such as …
[HTML][HTML] Androgen receptor structure, function and biology: from bench to bedside
The actions of androgens such as testosterone and dihydrotestosterone are mediated via
the androgen receptor (AR), a ligand-dependent nuclear transcription factor and member of …
the androgen receptor (AR), a ligand-dependent nuclear transcription factor and member of …
Non-genomic actions of androgens
Previous work in the endocrine and neuroendocrine fields has viewed the androgen
receptor (AR) as a transcription factor activated by testosterone or one of its many …
receptor (AR) as a transcription factor activated by testosterone or one of its many …
[HTML][HTML] The phytochemical, biological, and medicinal attributes of phytoecdysteroids: An updated review
N Das, SK Mishra, A Bishayee, ES Ali… - … Pharmaceutica Sinica B, 2021 - Elsevier
The phytoecdysteroids (PEs) comprise a large group of biologically-active plant steroids,
which have structures similar to those of insect-molting hormones. PEs are distributed in …
which have structures similar to those of insect-molting hormones. PEs are distributed in …
Prenatal androgen exposure causes hypertension and gut microbiota dysbiosis
Background: Conditions of excess androgen in women, such as polycystic ovary syndrome
(PCOS), often exhibit intergenerational transmission. One way in which the risk for PCOS …
(PCOS), often exhibit intergenerational transmission. One way in which the risk for PCOS …
Anabolic-androgenic steroids and cardiovascular risk
JD Liu, YQ Wu - Chinese medical journal, 2019 - mednexus.org
Objective: Anabolic-androgenic steroids (AAS) represents a group of synthetic testosterone
derivatives that play an important role in clinical treatment. These drugs are widely abused …
derivatives that play an important role in clinical treatment. These drugs are widely abused …
Apoptosis and autophagy: decoding calcium signals that mediate life or death
MW Harr, CW Distelhorst - Cold Spring Harbor …, 2010 - cshperspectives.cshlp.org
Calcium is a versatile and dynamic 2nd messenger that is essential for the survival of all
higher organisms. In cells that undergo activation or excitation, calcium is released from the …
higher organisms. In cells that undergo activation or excitation, calcium is released from the …
Rapid actions of androgens
G Michels, UC Hoppe - Frontiers in neuroendocrinology, 2008 - Elsevier
The biological activity of androgens is thought to occur predominantly through binding to
intracellular androgen-receptors, a member of the nuclear receptor family, that interact with …
intracellular androgen-receptors, a member of the nuclear receptor family, that interact with …
New insights in RBM20 cardiomyopathy
D Lennermann, J Backs… - Current heart failure …, 2020 - Springer
Abstract Purpose of Review This review aims to give an update on recent findings related to
the cardiac splicing factor RNA-binding motif protein 20 (RBM20) and RBM20 …
the cardiac splicing factor RNA-binding motif protein 20 (RBM20) and RBM20 …
Rapid steroid hormone actions initiated at the cell surface and the receptors that mediate them with an emphasis on recent progress in fish models
P Thomas - General and comparative endocrinology, 2012 - Elsevier
In addition to the classic genomic mechanism of steroid action mediated by activation of
intracellular nuclear receptors, there is now extensive evidence that steroids also activate …
intracellular nuclear receptors, there is now extensive evidence that steroids also activate …