Organoselenium compounds as mimics of selenoproteins and thiol modifier agents

NV Barbosa, CW Nogueira, PA Nogara… - Metallomics, 2017 - academic.oup.com
Selenium is an essential trace element for animals and its role in the chemistry of life relies
on a unique functional group: the selenol (–SeH) group. The selenol group participates in …

[HTML][HTML] Cellular and molecular mechanisms mediating methylmercury neurotoxicity and neuroinflammation

JP Novo, B Martins, RS Raposo, FC Pereira… - International journal of …, 2021 - mdpi.com
Methylmercury (MeHg) toxicity is a major environmental concern. In the aquatic reservoir,
MeHg bioaccumulates along the food chain until it is consumed by riverine populations …

Toxicity of ethylmercury (and Thimerosal): a comparison with methylmercury

JG Dórea, M Farina, JBT Rocha - Journal of Applied …, 2013 - Wiley Online Library
Ethylmercury (etHg) is derived from the metabolism of thimerosal (o‐carboxyphenyl‐thio‐
ethyl‐sodium salt), which is the most widely used form of organic mercury. Because of its …

[HTML][HTML] Neurotoxicity mechanism of aconitine in HT22 cells studied by microfluidic chip-mass spectrometry

Y Zhang, S Chen, F Fan, N Xu, XL Meng… - Journal of …, 2023 - Elsevier
Aconitine, a common and main toxic component of Aconitum, is toxic to the central nervous
system. However, the mechanism of aconitine neurotoxicity is not yet clear. In this work, we …

Advances on the influence of methylmercury exposure during neurodevelopment

J Pan, X Li, Y Wei, L Ni, B Xu, Y Deng… - Chemical Research …, 2022 - ACS Publications
Mercury (Hg) is a toxic heavy-metal element, which can be enriched in fauna and flora and
transformed into methylmercury (MeHg). MeHg is a widely distributed environmental …

Mitochondrial medicine: A promising therapeutic option against various neurodegenerative disorders

MA Almikhlafi, MM Karami, A Jana… - Current …, 2023 - benthamdirect.com
Abnormal mitochondrial morphology and metabolic dysfunction have been observed in
many neurodegenerative disorders (NDDs). Mitochondrial dysfunction can be caused by …

Milk thistle and co-enzyme Q10 fortified diets lessen the nickel chloride-induced neurotoxic and neurobehavioral impairments in Oreochromis niloticus via regulating …

AA Khalil, YM Abd-Elhakim, EN Said, AAA Moselhy… - Aquaculture, 2022 - Elsevier
This study was conducted to investigate the effect of milk thistle powder (MTP) and/or co-
enzyme Q10 (CoQ10) dietary supplementation on the neurobehavioral performance and …

MeHg-induced autophagy via JNK/Vps34 complex pathway promotes autophagosome accumulation and neuronal cell death

T Lin, S Ruan, D Huang, X Meng, W Li, B Wang… - Cell Death & …, 2019 - nature.com
Methylmercury (MeHg), an environmental toxin, may specifically cause neurological
disorders. Recent studies have reported that autophagy can be induced by metals and be …

Connexin hemichannels and pannexin channels in toxicity: Recent advances and mechanistic insights

D Yang, M Chen, S Yang, F Deng, X Guo - Toxicology, 2023 - Elsevier
Connexin hemichannels and pannexin channels are two types of transmembrane channels
that allow autocrine/paracrine signalling through the exchange of ions and molecules …

Into the deep: Exploring the molecular mechanisms of hyperactive behaviour induced by three rare earth elements in early life-stages of the deep-sea scavenging …

JA Riedel, I Smolina, C Donat, LH Svendheim… - Science of the Total …, 2024 - Elsevier
With increasing socio-economic importance of the rare earth elements and yttrium (REY),
Norway has laid out plans for REY mining, from land-based to deep-sea mining, thereby …