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Overcoming skin barriers through advanced transdermal drug delivery approaches
Upon exhaustive research, the transdermal drug delivery system (TDDS) has appeared as a
potential, well-accepted, and popular approach to a novel drug delivery system. Ease of …
potential, well-accepted, and popular approach to a novel drug delivery system. Ease of …
Improved topical drug delivery: Role of permeation enhancers and advanced approaches
The delivery of drugs via transdermal routes is an attractive approach due to ease of
administration, bypassing of the first-pass metabolism, and the large skin surface area …
administration, bypassing of the first-pass metabolism, and the large skin surface area …
Development and optimization of curcumin analog nano-bilosomes using 21.31 full factorial design for anti-tumor profiles improvement in human hepatocellular …
Curcumin (CU) is a natural polyphenolic phytoingredient. CU has anti-inflammatory, anti-
oxidant, and anticancer activities. The poor solubility, bioavailability, and stability of CU …
oxidant, and anticancer activities. The poor solubility, bioavailability, and stability of CU …
A brain-targeted approach to ameliorate memory disorders in a sporadic alzheimer's disease mouse model via intranasal luteolin-loaded nanobilosomes
Impaired memory and cognitive function are the main features of Alzheimer's disease (AD).
Unfortunately, currently available treatments cannot cure or delay AD progression …
Unfortunately, currently available treatments cannot cure or delay AD progression …
Challenges of current treatment and exploring the future prospects of nanoformulations for treatment of atopic dermatitis
Atopic dermatitis (AD) is a predominant and deteriorating chronic inflammation of the skin,
categorized by a burning sensation and eczematous lesions in diverse portions of the body …
categorized by a burning sensation and eczematous lesions in diverse portions of the body …
Full factorial design, physicochemical characterization, ex vivo investigation, and biological assessment of glutathione-loaded solid lipid nanoparticles for topical …
Abstract l-Glutathione (GSH) has exceptional antioxidant activities against UVA irradiation-
induced oxidative stress and is used widely for combatting skin ageing. However, topical …
induced oxidative stress and is used widely for combatting skin ageing. However, topical …
Recent updates on applications of lipid-based nanoparticles for site-specific drug delivery
Background: Site-specific drug delivery is a widespread and demanding area nowadays.
Lipid-based nanoparticulate drug delivery systems have shown promising effects for …
Lipid-based nanoparticulate drug delivery systems have shown promising effects for …
Fabrication, optimization, and evaluation of lyophilized lacidipine-loaded fatty-based nanovesicles as orally fast disintegrating sponge delivery system
Lacidipine (LCD) is a potent antihypertensive agent. Fatty-based nanovesicles (FNVs) were
designed to improve LCD low solubility and bioavailability. LCD-FNVs were formulated …
designed to improve LCD low solubility and bioavailability. LCD-FNVs were formulated …
Potential strategy of microneedle-based transdermal drug delivery system for effective management of skin-related immune disorders
P Xu, W **ao, K Xu, Y He, X Miao, Y Dong… - European Journal of …, 2024 - Elsevier
Skin-related immune disorders are a category of diseases that lead to the dysregulation of
the body's immune response due to imbalanced immune regulation. These disorders exhibit …
the body's immune response due to imbalanced immune regulation. These disorders exhibit …
Cutaneous pharmacokinetics of topically applied novel dermatological formulations
Novel formulations are developed for dermatological applications to address a wide range
of patient needs and therapeutic challenges. By pushing the limits of pharmaceutical …
of patient needs and therapeutic challenges. By pushing the limits of pharmaceutical …