Accumulation of excess iron in the body, or systemic iron overload, results from a variety of
causes. The concentration of iron in the liver is linearly related to the total body iron stores …

Magnetic susceptibility describes the magnetizability of a material to an applied magnetic
field and represents an important parameter in the field of MRI. With the recently introduced …

Liver iron overload is the histological hallmark of hereditary hemochromatosis and
transfusional hemosiderosis, and can also occur in chronic hepatopathies. Iron overload can …

Measurement of liver iron concentration (LIC) is necessary for a range of iron-loading
disorders such as hereditary hemochromatosis, thalassemia, sickle cell disease, aplastic …

Purpose To describe and demonstrate the feasibility of a novel multiecho reconstruction
technique that achieves simultaneous water‐fat decomposition and T2* estimation. The …

The sickle hemoglobin is an abnormal hemoglobin due to point mutation (GAG→ GTG) in
exon 1 of the β globin gene resulting in the substitution of glutamic acid by valine at position …

Iron overload is the histological hallmark of genetic hemochromatosis and transfusional
hemosiderosis but also may occur in chronic hepatopathies. This article provides an …

Purpose: The purpose of this work was to develop and demonstrate feasibility and initial
clinical validation of quantitative susceptibility map** (QSM) in the abdomen as an …

Liver biopsy is the standard test for the assessment of fibrosis in liver tissue of patients with
chronic liver disease. Recent studies have used a non‐invasive measure of T1 relaxation …

Background—Transfusional therapy for thalassemia major and sickle cell disease can lead
to iron deposition and damage to the heart, liver, and endocrine organs. Iron causes the MRI …