A growing understanding of the benefits of exercise over the past few decades has
prompted researchers to take an interest in the possibilities of exercise therapy. Because …

The identification of the human cannabinoid receptors and their roles in health and disease,
has been one of the most significant biochemical and pharmacological advancements to …

Heart failure (HF) is a complex clinical syndrome with multiple interactions between the
failing myocardium and cerebral (dys‐) functions. Bi‐directional feedback interactions …

Background The role of exercise training modality to attenuate left ventricular (LV)
remodeling in heart failure patients with reduced ejection fraction (HFrEF) remains …

A large body of evidence exists indicating that autonomic imbalance is characteristic of heart
failure, with several parameters of autonomic function associated with adverse clinical …

The control of ventilation and cardiovascular function during physical activity is partially
regulated by the ergoreflex, a cardiorespiratory reflex activated by physical activity. Two …

Although aerobic exercise training has shown to be an effective treatment for chronic heart
failure patients, there has been a debate about the design of training programs and which …

In our original white paper published in the The Journal of Physiology in 2016, we set out
our knowledge of the structural and functional organization of cardiac autonomic control …

Sympathetic activation is a consistent finding in the chronic heart failure (CHF) state. Current
therapy for CHF targets the renin-angiotensin II (ANG II) and adrenergic systems …

Exercise capacity in adults with various forms of congenital heart disease is substantially
lower than that of the general population. Although the underlying congenital heart defect …