Emerging trends in post-translational modification: Shedding light on Glioblastoma multiforme

S Kumari, R Gupta, RK Ambasta, P Kumar - Biochimica et Biophysica Acta …, 2023 - Elsevier
Recent multi-omics studies, including proteomics, transcriptomics, genomics, and
metabolomics have revealed the critical role of post-translational modifications (PTMs) in the …

ACP-MHCNN: an accurate multi-headed deep-convolutional neural network to predict anticancer peptides

S Ahmed, R Muhammod, ZH Khan, S Adilina… - Scientific reports, 2021 - nature.com
Although advancing the therapeutic alternatives for treating deadly cancers has gained
much attention globally, still the primary methods such as chemotherapy have significant …

Analysis and review of techniques and tools based on machine learning and deep learning for prediction of lysine malonylation sites in protein sequences

S Ramazi, SAH Tabatabaei, E Khalili, AG Nia… - Database, 2024 - academic.oup.com
The post-translational modifications occur as crucial molecular regulatory mechanisms
utilized to regulate diverse cellular processes. Malonylation of proteins, a reversible post …

CNN-Pred: Prediction of single-stranded and double-stranded DNA-binding protein using convolutional neural networks

F Manavi, A Sharma, R Sharma, T Tsunoda… - Gene, 2023 - Elsevier
DNA-binding proteins play a vital role in biological activity including DNA replication, DNA
packing, and DNA reparation. DNA-binding proteins can be classified into single-stranded …

Spppred: Sequence-based protein-peptide binding residue prediction using genetic programming and ensemble learning

S Shafiee, A Fathi, G Taherzadeh - IEEE/ACM Transactions on …, 2022 - ieeexplore.ieee.org
Peptide-binding proteins play significant roles in various applications such as gene
expression, metabolism, signal transmission, DNA (Deoxyribose Nucleic Acid) repair, and …

Substrate and Functional Diversity of Protein Lysine Post-translational Modifications

B Hao, K Chen, L Zhai, M Liu, B Liu… - Genomics, Proteomics & …, 2024 - academic.oup.com
Lysine post-translational modifications (PTMs) are widespread and versatile protein PTMs
that are involved in diverse biological processes by regulating the fundamental functions of …

Accurate Prediction of Lysine Methylation Sites Using Evolutionary and Structural-Based Information

ME Arafat, MW Ahmad, SM Shovan, TU Haq… - Cognitive …, 2024 - Springer
Methylation is considered one of the proteins' most important post-translational modifications
(PTM). Plasticity and cellular dynamics are among the many traits that are regulated by …

DeepPhoPred: Accurate Deep Learning Model to Predict Microbial Phosphorylation

F Ahmed, A Sharma, S Shatabda… - … Structure, Function, and …, 2025 - Wiley Online Library
Phosphorylation is a substantial posttranslational modification of proteins that refers to
adding a phosphate group to the amino acid side chain after translation process in the …

iProtGly-SS: a tool to accurately predict protein glycation site using structural-based features

I Dehzangi, A Sharma, S Shatabda - Computational Methods for Predicting …, 2022 - Springer
Posttranslational modification (PTM) is an important biological mechanism to promote
functional diversity among the proteins. So far, a wide range of PTMs has been identified …

Predicting lysine methylation sites using a convolutional neural network

A Spadaro, A Sharma, I Dehzangi - Methods, 2024 - Elsevier
Protein lysine methylation is a particular type of post translational modification that plays an
important role in both histone and non-histone function regulation in proteins. Deregulation …