Deleterious effect of gestagens from wastewater effluent on fish reproduction in aquatic environment: A review

JS Jenila, PK Issac, SS Lam, JC Oviya, S Jones… - Environmental …, 2023 - Elsevier
Gestagens are common pollutants accumulated in the aquatic ecosystem. Gestagens are
comprised of natural gestagens (ie progesterone) and synthetic gestagens (ie progestins) …

The impact of co-exposure to polystyrene microplastics and norethindrone on gill histology, antioxidant capacity, reproductive system, and gut microbiota in zebrafish …

S Zhou, H Lin, Z Liu, X Lian, CG Pan, Z Dong, Z Lin… - Aquatic Toxicology, 2024 - Elsevier
In recent years, studies have focused on the combined ecological risks posed by
microplastics and other organic pollutants. Although both microplastics and progestin …

The progestin norethindrone alters growth, reproductive histology and gene expression in zebrafish (Danio rerio)

YQ Liang, Z **g, CG Pan, Z Lin, Z Zhen, L Hou… - Chemosphere, 2020 - Elsevier
The aim of this study was to assess the long-term effects of synthetic progestin
norethindrone (NET) on the growth, reproductive histology, and transcriptional expression …

The interactive effects of ethinylestradiol and progesterone on transcriptional expression of genes along the hypothalamus–pituitary–thyroid axis in embryonic …

J Tan, H Chen, S Chen, J Hu, X Wang, Y Wang… - Science of The Total …, 2022 - Elsevier
Progestins and estrogens are widespread in various aquatic environments and their
potential endocrine disruption effects to aquatic organisms have drawn growing concern …

Norethindrone causes cellular and hepatic injury in zebrafish by compromising the metabolic processes associated with antioxidant defence: Insights from …

X Wang, Z Tan, S Chen, L Gui, X Li, D Ke, L Hou… - Chemosphere, 2021 - Elsevier
Progestins, such as norethindrone (NET), have been increasingly detected in aquatic
environments due to their extensive use for medical applications. While NET is notorious for …

Norethindrone alters growth, sex differentiation and gene expression in marine medaka (Oryzias melastigma)

Z Dong, Y Chen, X Li, N Zhang, Y Guo… - Environmental …, 2022 - Wiley Online Library
Norethindrone (NET) is a widely used synthetic progestin, which appears in water
environments and threatens aquatic organisms. In this study, marine medaka (Oryzias …

Effects of dexamethasone on the morphology, gene expression and hepatic histology in adult female mosquitofish (Gambusia affinis)

L Zhong, YQ Liang, M Lu, CG Pan, Z Dong, H Zhao… - Chemosphere, 2021 - Elsevier
Glucocorticoids (GCs), including natural hormones as well as synthetic chemicals, can pose
influences on physiological performance, development and reproduction of fish …

Short-term exposure to norethisterone affected swimming behavior and antioxidant enzyme activity of medaka larvae, and led to masculinization in the adult …

Z Dong, X Li, Y Chen, N Zhang, Z Wang, YQ Liang… - Chemosphere, 2023 - Elsevier
Norethisterone (NET), one of the synthetic progestins, is detected with increasing frequency
in the water environment and distributed in the ocean, with a potential toxicity risk to marine …

The synthetic progestin norethindrone causes thyroid endocrine disruption in adult zebrafish

YQ Liang, W Xu, X Liang, Z **g, CG Pan… - … and Physiology Part C …, 2020 - Elsevier
Synthetic progestin norethindrone (NET) widely used in oral contraceptives, hormonal
therapy and livestock farming has been detected in various aquatic ecosystems. Recent …

[HTML][HTML] Endocrine disrupting effects of binary mixtures of 17β-estradiol and testosterone in adult female western mosquitofish (Gambusia affinis)

GZ Fang, GY Huang, GG Ying, SQ Qiu, WJ Shi… - Ecotoxicology and …, 2021 - Elsevier
Androgens and estrogens often co-exist in aquatic environments and pose potential risks to
fish populations. However, little is known about the endocrine disrupting effects of the …