Emerging evidence now indicates that mitochondria are central regulators of neural stem
cell (NSC) fate decisions and are crucial for both neurodevelopment and adult …

Until recently, radiation effects have been considered to be mainly due to nuclear DNA
damage and their management by repair mechanisms. However, molecular biology studies …

Many people around the world suffer from some form of paralysis caused by spinal cord
injury (SCI), which has an impact on quality and life expectancy. The spinal cord is part of …

Reprogramming somatic cells to a pluripotent state drastically reconfigures the cellular
anabolic requirements, thus potentially inducing cancer-like metabolic transformation …

The importance of mitochondria in energy metabolism, signal transduction and aging in post-
mitotic tissues has been well established. Recently, the crucial role of mitochondrial-linked …

Mitochondria are classically known to be the cellular energy producers, but a renewed
appreciation for these organelles has developed with the accumulating discoveries of …

Mitochondria have been largely described as the powerhouse of the cell and recent findings
demonstrate that this organelle is fundamental for neurogenesis. The mechanisms …

Blood vessels are part of the stem cell niche in the develo** cerebral cortex, but their in
vivo role in controlling the expansion and differentiation of neural stem cells (NSC s) in …

Various stem cells gradually turned to be critical players in tissue engineering and
regenerative medicine therapies. Current evidence has demonstrated that in addition to …

As one of the most vital organelles within biological cells, mitochondria hold an
irreplaceable status and play crucial roles in various diseases. Research and therapies …