Melatonin protects the electron transport chain (ETC) in multiple ways. It reduces levels of·
NO by downregulating inducible and inhibiting neuronal nitric oxide synthases (iNOS …

Oxidative and nitrosative stress are common problems when handling gametes in vitro. In
vitro development in mammalian embryos is highly affected by culture conditions, especially …

Simple Summary The emergence of nanotechnology paves the way for innovating countless
applications in the agricultural and livestock production sector. In the field of reproductive …

The use of nanosized particles has emerged to facilitate selective applications in medicine.
Drug-delivery systems represent novel opportunities to provide stricter, focused, and fine …

Background Palmitic acid (PA), the main component of dietary saturated fat, causes
apoptosis in many cell types, including mouse granulosa cell. Melatonin, an important …

The present study investigated the effects of melatonin on bovine oocyte maturation and
subsequent embryonic development in vitro. Results showed that the nuclear and …

Simple Summary Exogenous melatonin has beneficial effects on improving cumulus
oophorus expansion; mitochondrial distribution; intracellular level of glutathione; and first …

Assisted reproductive technology (ART) have contributed to preserve fertility in humans and
to increase multiplication of genetically superior animals. Despite being highly practiced …

Reactive oxygen species (ROS) are one of the factors which reduces oocyte quality and
viability of the in vitro produced embryos. Oocyte mitochondria are the major source of ROS …

In this study, the potential of melatonin hormone loaded in nanostructured lipid carriers (Mel-
NLCs) in the in vitro fertilization (IVF) environment is investigated by measuring the oocyte …