Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder with a
worldwide prevalence of about 1%, characterized by impairments in social interaction …

Mice and rats emit ultrasonic vocalizations (USVs), which may express their arousal and
emotional states, to communicate with each other. There is continued scientific effort to …

The analysis of animal models of neurological disease has been instrumental in furthering
our understanding of neurodevelopment and brain diseases. However, animal models are …

Abstract Fragile X Syndrome (FXS) is the most common heritable form of mental retardation
and monogenic cause of autism spectrum disorder (ASD). FXS is due to a mutation in the X …

Autism spectrum disorders (ASD) are complex neurodevelopmental disorders that are
caused by genetic and/or environmental impacts, often probably by the interaction of both …

Clinical and preclinical findings have suggested a role of the endocannabinoid system
(ECS) in the etiopathology of autism spectrum disorder (ASD). Previous mouse studies have …

The precise anatomical degree of brain X chromosome inactivation (XCI) that is sufficient to
alter X-linked disorders in females is unclear. Here, we quantify whole-brain XCI at single …

Fragile X syndrome (FXS) is an X-linked neurodevelopmental disorder characterized by
several behavioral abnormalities, including hyperactivity, anxiety, sensory hyper …

Hyperacusis, ie, an increased sensitivity to sounds, is described in several
neurodevelopmental disorders (NDDs), including Fragile X Syndrome (FXS). The …

Fragile X syndrome (FXS) is a major neurodevelopmental disorder and the most common
monogenic cause of autism spectrum disorder (ASD). FXS is caused by a mutation in the X …