Impact of marine chemical ecology research on the discovery and development of new pharmaceuticals

LT Tan - Marine Drugs, 2023 - mdpi.com
Diverse ecologically important metabolites, such as allelochemicals, infochemicals and
volatile organic chemicals, are involved in marine organismal interactions. Chemically …

[HTML][HTML] Beyond the paclitaxel and vinca alkaloids: Next generation of plant-derived microtubule-targeting agents with potential anticancer activity

D Zhang, A Kanakkanthara - Cancers, 2020 - mdpi.com
Plants are an important source of chemically diverse natural products that target
microtubules, one of the most successful targets in cancer therapy. Colchicine, paclitaxel …

Marine mollusk‐derived agents with antiproliferative activity as promising anticancer agents to overcome chemotherapy resistance

ML Ciavatta, F Lefranc, M Carbone… - Medicinal Research …, 2017 - Wiley Online Library
The chemical investigation of marine mollusks has led to the isolation of a wide variety of
bioactive metabolites, which evolved in marine organisms as favorable adaptations to …

Bioprospecting marine plankton

H Abida, S Ruchaud, L Rios, A Humeau, I Probert… - Marine Drugs, 2013 - mdpi.com
The ocean dominates the surface of our planet and plays a major role in regulating the
biosphere. For example, the microscopic photosynthetic organisms living within provide …

Marine chemical ecology in benthic environments

MP Puglisi, JM Sneed, R Ritson-Williams… - Natural Product …, 2019 - pubs.rsc.org
Marine chemical ecology in benthic environments - Natural Product Reports (RSC Publishing)
DOI:10.1039/C8NP00061A Royal Society of Chemistry View PDF VersionPrevious ArticleNext …

[HTML][HTML] Bioactive prenyl-and terpenyl-quinones/hydroquinones of marine origin

PA García, ÁP Hernández, A San Feliciano, MÁ Castro - Marine drugs, 2018 - mdpi.com
The sea is a rich source of biological active compounds, among which terpenyl-quinones/
hydroquinones constitute a family of secondary metabolites with diverse pharmacological …

Polybrominated diphenyl ethers with potent and broad spectrum antimicrobial activity from the marine sponge Dysidea

S Sun, CB Canning, K Bhargava, X Sun, W Zhu… - Bioorganic & medicinal …, 2015 - Elsevier
Abstract Three polybrominated diphenyl ethers, 2-(2′, 4′-dibromophenoxy)-3, 5-
dibromophenol (1) and 2-(2′, 4′-dibromophenoxy)-3, 4, 5-tribromophenol (2) were …

Marine-derived antimicrobial molecules from the sponges and their associated bacteria

HU Devkar, NL Thakur, P Kaur - Canadian Journal of …, 2022 - cdnsciencepub.com
Antimicrobial resistance (AMR) is one of the leading global health issues that demand
urgent attention. Very soon the world will have to bear the consequences of increased drug …

Metabolome variability for two Mediterranean sponge species of the genus Haliclona: specificity, time, and space

M Reverter, MA Tribalat, T Pérez, OP Thomas - Metabolomics, 2018 - Springer
Introduction The study of natural variation of metabolites brings valuable information on the
physiological state of the organisms as well as their phenotypic traits. In marine organisms …

Contact-free impacts of sessile reef organisms on stony coral productivity

KE Engelhardt, J Vetter, F Wöhrmann-Zipf… - … Earth & Environment, 2023 - nature.com
Coral reefs are biodiversity and productivity hotspots where space limitation makes
interactions between organisms inevitable. Biodiversity loss alters these interactions …