Guidelines for the use of an insulin infusion for the management of hyperglycemia in critically ill patients
Objective: To evaluate the literature and identify important aspects of insulin therapy that
facilitate safe and effective infusion therapy for a defined glycemic end point. Methods:
facilitate safe and effective infusion therapy for a defined glycemic end point. Methods:
[HTML][HTML] Stress-induced hyperglycemia: consequences and management
D Vedantam, DS Poman, L Motwani, N Asif, A Patel… - Cureus, 2022 - ncbi.nlm.nih.gov
Hyperglycemia during stress is a common occurrence seen in patients admitted to the
hospital. It is defined as a blood glucose level above 180mg/dl in patients without pre …
hospital. It is defined as a blood glucose level above 180mg/dl in patients without pre …
Time in blood glucose range 70 to 140 mg/dl> 80% is strongly associated with increased survival in non-diabetic critically ill adults
JS Krinsley, JC Preiser - Critical care, 2015 - Springer
Introduction Hyperglycemia, hypoglycemia and increased glucose variability are
independently associated with increased risk of death in critically ill adults. The relationship …
independently associated with increased risk of death in critically ill adults. The relationship …
A physiological Intensive Control Insulin-Nutrition-Glucose (ICING) model validated in critically ill patients
Intensive insulin therapy (IIT) and tight glycaemic control (TGC), particularly in intensive care
unit (ICU), are the subjects of increasing and controversial debate in recent years. Model …
unit (ICU), are the subjects of increasing and controversial debate in recent years. Model …
Safety, efficacy and clinical generalization of the STAR protocol: a retrospective analysis
Background The changes in metabolic pathways and metabolites due to critical illness result
in a highly complex and dynamic metabolic state, making safe, effective management of …
in a highly complex and dynamic metabolic state, making safe, effective management of …
Glucose variability measures and their effect on mortality: a systematic review
Objective To systematically review the medical literature on the association between
glucose variability measures and mortality in critically ill patients. Methods Studies …
glucose variability measures and mortality in critically ill patients. Methods Studies …
Feasibility of fully automated closed-loop glucose control using continuous subcutaneous glucose measurements in critical illness: a randomized controlled trial
Introduction Closed-loop (CL) systems modulate insulin delivery according to glucose levels
without nurse input. In a prospective randomized controlled trial, we evaluated the feasibility …
without nurse input. In a prospective randomized controlled trial, we evaluated the feasibility …
STAR development and protocol comparison
LM Fisk, AJ Le Compte, GM Shaw… - IEEE Transactions …, 2012 - ieeexplore.ieee.org
Accurate glycemic control (AGC) is difficult due to excessive hypoglycemia risk. Stochastic
TARgeted (STAR) glycemic control forecasts changes in insulin sensitivity to calculate a …
TARgeted (STAR) glycemic control forecasts changes in insulin sensitivity to calculate a …
Tight glycemic control in critical care–the leading role of insulin sensitivity and patient variability: a review and model-based analysis
Tight glycemic control (TGC) has emerged as a major research focus in critical care due to
its potential to simultaneously reduce both mortality and costs. However, repeating initial …
its potential to simultaneously reduce both mortality and costs. However, repeating initial …
Stochastic targeted (STAR) glycemic control: design, safety, and performance
A Evans, A Le Compte, CS Tan… - Journal of diabetes …, 2012 - journals.sagepub.com
Introduction: Tight glycemic control (TGC) has shown benefits but has been difficult to
achieve consistently. STAR (Stochastic TARgeted) is a flexible, model-based TGC approach …
achieve consistently. STAR (Stochastic TARgeted) is a flexible, model-based TGC approach …